Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Erdosteine> ?p ?o. }
Showing items 1 to 71 of
71
with 100 items per page.
- Erdosteine abstract "Erdosteine is a mucolytic. Specifically it is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains two blocked sulfhydryl groups which are released following first-pass metabolism. The three active metabolites exhibit mucolytic and free radical scavenging activity. Erdosteine modulates mucus production and viscosity and increases mucociliary transport, thereby improving expectoration. It also exhibits inhibitory activity against the effects of free radicals produced by cigarette smoke.Clinical studies in patients with chronic obstructive lung disease have demonstrated the efficacy and tolerability of erdosteine.Template:Drugs Exp Clin Res. 2004;30(4):143-52.The effect of long-term treatment with erdosteine on chronic obstructive pulmonary disease: the EQUALIFE Study. Erdosteine 300 mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sputum more effectively than bromhexine 30 mg twice daily.[citation needed]Co-administration of erdosteine and amoxicillin in patients with acute infective exacerbation of chronic bronchitis resulted in higher concentrations of the antibiotic in the sputum, leading to earlier and more pronounced amelioration of clinical symptoms compared with placebo.[citation needed]Erdosteine is associated with a low incidence of adverse events, most of which are gastrointestinal and generally mild. The LD50 is very high, 3,500-5,000 mg/kg.Tradenames used in Europe:ErdomedErdopectErdostinErdotinEvostenMucodoxMucoforTheovixTusselinVectrineApart from the Tradenames listed above, in other regions of the world the product is also marketed under:AsdiganBiopulminDosteinDostinDostolEctrinEdotinErdosEsteclinFluidasaMucofluxMucotecMukialZertin".
- Erdosteine atcPrefix "R05".
- Erdosteine atcSuffix "CB15".
- Erdosteine casNumber "84611-23-4".
- Erdosteine fdaUniiCode "76J0853EKA".
- Erdosteine iupacName "2-[(2-oxothiolan-3-yl)carbamoylmethylsulfanyl]acetic acid".
- Erdosteine pubchem "65632".
- Erdosteine thumbnail Erdosteine.png?width=300.
- Erdosteine wikiPageID "12285532".
- Erdosteine wikiPageRevisionID "584906027".
- Erdosteine atcPrefix "R05".
- Erdosteine atcSuffix "CB15".
- Erdosteine c "8".
- Erdosteine casNumber "84611".
- Erdosteine chemspiderid "59073".
- Erdosteine eliminationHalfLife "-10800.0".
- Erdosteine h "11".
- Erdosteine hasPhotoCollection Erdosteine.
- Erdosteine inchi "1".
- Erdosteine inchikey "QGFORSXNKQLDNO-UHFFFAOYAW".
- Erdosteine iupacName "2".
- Erdosteine kegg "D07383".
- Erdosteine metabolism "hepatic".
- Erdosteine molecularWeight "249.309".
- Erdosteine n "1".
- Erdosteine o "4".
- Erdosteine proteinBound "65.0".
- Erdosteine pubchem "65632".
- Erdosteine routesOfAdministration "oral, inhalation".
- Erdosteine s "2".
- Erdosteine smiles "O=C1SCCC1NCCSCCO".
- Erdosteine stdinchi "1".
- Erdosteine stdinchikey "QGFORSXNKQLDNO-UHFFFAOYSA-N".
- Erdosteine unii "76".
- Erdosteine verifiedrevid "447814556".
- Erdosteine subject Category:Amides.
- Erdosteine subject Category:Antitussives.
- Erdosteine subject Category:Carboxylic_acids.
- Erdosteine subject Category:Thioethers.
- Erdosteine subject Category:Thiolactones.
- Erdosteine type Abstraction100002137.
- Erdosteine type Acid114607521.
- Erdosteine type Amide114724264.
- Erdosteine type Amides.
- Erdosteine type CarboxylicAcid114739360.
- Erdosteine type CarboxylicAcids.
- Erdosteine type Chemical114806838.
- Erdosteine type Compound114818238.
- Erdosteine type Material114580897.
- Erdosteine type Matter100020827.
- Erdosteine type OrganicCompound114727670.
- Erdosteine type Part113809207.
- Erdosteine type PhysicalEntity100001930.
- Erdosteine type Relation100031921.
- Erdosteine type Substance100019613.
- Erdosteine type Drug.
- Erdosteine type DrugProduct.
- Erdosteine type FunctionalSubstance.
- Erdosteine comment "Erdosteine is a mucolytic. Specifically it is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains two blocked sulfhydryl groups which are released following first-pass metabolism. The three active metabolites exhibit mucolytic and free radical scavenging activity. Erdosteine modulates mucus production and viscosity and increases mucociliary transport, thereby improving expectoration.".
- Erdosteine label "Erdosteina".
- Erdosteine label "Erdosteina".
- Erdosteine label "Erdosteine".
- Erdosteine sameAs Erdosteina.
- Erdosteine sameAs Erdosteina.
- Erdosteine sameAs m.02vyztt.
- Erdosteine sameAs Q3731252.
- Erdosteine sameAs Q3731252.
- Erdosteine sameAs Erdosteine.
- Erdosteine wasDerivedFrom Erdosteine?oldid=584906027.
- Erdosteine depiction Erdosteine.png.
- Erdosteine isPrimaryTopicOf Erdosteine.
