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- Excisionase abstract "In molecular biology, excisionase is a bacteriophage protein encoded by the Xis gene. It is involved in excisive recombination by regulating the assembly of the excisive intasome and by inhibiting viral integration. It adopts an unusual winged-helix structure in which two alpha helices are packed against two extended strands. Also present in the structure is a two-stranded anti-parallel beta-sheet, whose strands are connected by a four-residue wing. During interaction with DNA, helix alpha2 is thought to insert into the major groove, while the wing contacts the adjacent minor groove or phosphodiester backbone. The C-terminal region of excisionase is involved in interaction with phage-encoded integrase (Int), and a putative C-terminal alpha helix may fold upon interaction with Int and/or DNA.".
- Excisionase symbol "Exc".
- Excisionase thumbnail PDB_2og0_EBI.jpg?width=300.
- Excisionase wikiPageID "32713971".
- Excisionase wikiPageRevisionID "591247159".
- Excisionase caption "crystal structure of the lambda xis-dna complex".
- Excisionase hasPhotoCollection Excisionase.
- Excisionase interpro "IPR012884".
- Excisionase name "Excisionase-like protein".
- Excisionase pfam "PF07825".
- Excisionase pfamClan "CL0123".
- Excisionase symbol "Exc".
- Excisionase tcdb "2".
- Excisionase subject Category:Protein_domains.
- Excisionase type Abstraction100002137.
- Excisionase type Attribute100024264.
- Excisionase type Environment113934596.
- Excisionase type ProteinDomains.
- Excisionase type Situation113927383.
- Excisionase type Sphere114514039.
- Excisionase type State100024720.
- Excisionase type Biomolecule.
- Excisionase type Protein.
- Excisionase type BiologicalObject.
- Excisionase comment "In molecular biology, excisionase is a bacteriophage protein encoded by the Xis gene. It is involved in excisive recombination by regulating the assembly of the excisive intasome and by inhibiting viral integration. It adopts an unusual winged-helix structure in which two alpha helices are packed against two extended strands. Also present in the structure is a two-stranded anti-parallel beta-sheet, whose strands are connected by a four-residue wing.".
- Excisionase label "Excisionase".
- Excisionase sameAs m.0h3mmwp.
- Excisionase sameAs Q5419626.
- Excisionase sameAs Q5419626.
- Excisionase sameAs Excisionase.
- Excisionase wasDerivedFrom Excisionase?oldid=591247159.
- Excisionase depiction PDB_2og0_EBI.jpg.
- Excisionase isPrimaryTopicOf Excisionase.