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- Exosome_component_6 abstract "Exosome complex exonuclease MTR3 is an enzyme that in humans is encoded by the EXOSC6 gene.This gene product constitutes one of the subunits of the multisubunit particle called the exosome complex, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.".
- Exosome_component_6 entrezgene "118460".
- Exosome_component_6 wikiPageID "16846219".
- Exosome_component_6 wikiPageRevisionID "591266794".
- Exosome_component_6 hasPhotoCollection Exosome_component_6.
- Exosome_component_6 requireManualInspection "no".
- Exosome_component_6 summaryText "This gene product constitutes one of the subunits of the multisubunit particle called the exosome complex, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements , but not for poly shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.".
- Exosome_component_6 updateCitations "yes".
- Exosome_component_6 updatePage "yes".
- Exosome_component_6 updateProteinBox "yes".
- Exosome_component_6 updateSummary "yes".
- Exosome_component_6 type Biomolecule.
- Exosome_component_6 type Protein.
- Exosome_component_6 type BiologicalObject.
- Exosome_component_6 comment "Exosome complex exonuclease MTR3 is an enzyme that in humans is encoded by the EXOSC6 gene.This gene product constitutes one of the subunits of the multisubunit particle called the exosome complex, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein.".
- Exosome_component_6 label "Exosome component 6".
- Exosome_component_6 sameAs m.04083_6.
- Exosome_component_6 sameAs Q5420685.
- Exosome_component_6 sameAs Q5420685.
- Exosome_component_6 wasDerivedFrom Exosome_component_6?oldid=591266794.
- Exosome_component_6 isPrimaryTopicOf Exosome_component_6.