Matches in DBpedia 2014 for { <http://dbpedia.org/resource/FGFRL1> ?p ?o. }
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- FGFRL1 abstract "Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene.The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.".
- FGFRL1 entrezgene "53834".
- FGFRL1 wikiPageID "14880943".
- FGFRL1 wikiPageRevisionID "435154425".
- FGFRL1 hasPhotoCollection FGFRL1.
- FGFRL1 requireManualInspection "no".
- FGFRL1 summaryText "The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.".
- FGFRL1 updateCitations "yes".
- FGFRL1 updatePage "yes".
- FGFRL1 updateProteinBox "yes".
- FGFRL1 updateSummary "yes".
- FGFRL1 type Biomolecule.
- FGFRL1 type Protein.
- FGFRL1 type BiologicalObject.
- FGFRL1 comment "Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene.The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution.".
- FGFRL1 label "FGFRL1".
- FGFRL1 sameAs m.03h06q8.
- FGFRL1 sameAs Q5425486.
- FGFRL1 sameAs Q5425486.
- FGFRL1 wasDerivedFrom FGFRL1?oldid=435154425.
- FGFRL1 isPrimaryTopicOf FGFRL1.