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- FOLFIRI abstract "FOLFIRI is a chemotherapy regimen for treatment of colorectal cancer. It is made up of the following drugs: FOL – folinic acid (leucovorin), a vitamin B derivative used as a "rescue" drug for high doses of the drug methotrexate, but increases the cytotoxicity of 5-fluorouracil; F – fluorouracil (5-FU), a pyrimidine analog and antimetabolite which incorporates into the DNA molecule and stops synthesis; and IRI – irinotecan (Camptosar), a topoisomerase inhibitor, which prevents DNA from uncoiling and duplicating. Several drugs, including Cetuximab, a monoclonal antibody to epidermal growth factor receptor, are sometimes added to FOLFIRI.The regimen consists of: Irinotecan (180 mg/m² IV over 90 minutes) concurrently with folinic acid (400 mg/m² [or 2 x 250 mg/m²] IV over 120 minutes). Followed by fluorouracil (400–500 mg/m² IV bolus) then fluorouracil (2400–3000 mg/m² intravenous infusion over 46 hours).This cycle is typically repeated every two weeks. The dosages shown above may vary from cycle to cycle.".
- FOLFIRI wikiPageID "5179897".
- FOLFIRI wikiPageRevisionID "588821693".
- FOLFIRI hasPhotoCollection FOLFIRI.
- FOLFIRI subject Category:Chemotherapy_regimens.
- FOLFIRI type Abstraction100002137.
- FOLFIRI type Act100030358.
- FOLFIRI type Activity100407535.
- FOLFIRI type CancerTreatments.
- FOLFIRI type Care100654885.
- FOLFIRI type ChemotherapyRegimens.
- FOLFIRI type Cognition100023271.
- FOLFIRI type Content105809192.
- FOLFIRI type Event100029378.
- FOLFIRI type Idea105833840.
- FOLFIRI type Plan105898568.
- FOLFIRI type PsychologicalFeature100023100.
- FOLFIRI type Regimen105909585.
- FOLFIRI type Treatment100658082.
- FOLFIRI type Work100575741.
- FOLFIRI type YagoPermanentlyLocatedEntity.
- FOLFIRI comment "FOLFIRI is a chemotherapy regimen for treatment of colorectal cancer.".
- FOLFIRI label "FOLFIRI".
- FOLFIRI label "FOLFIRI".
- FOLFIRI label "FOLFIRI".
- FOLFIRI sameAs FOLFIRI.
- FOLFIRI sameAs FOLFIRI.
- FOLFIRI sameAs m.0d6j9y.
- FOLFIRI sameAs Q1389369.
- FOLFIRI sameAs Q1389369.
- FOLFIRI sameAs FOLFIRI.
- FOLFIRI wasDerivedFrom FOLFIRI?oldid=588821693.
- FOLFIRI isPrimaryTopicOf FOLFIRI.