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- Factor_H abstract "Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at typical concentrations of 200–300 micrograms per milliliter). Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses, because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not, normally, on pathogen surfaces.".
- Factor_H entrezgene "3075".
- Factor_H thumbnail Model_of_factorH-C3b_complex.png?width=300.
- Factor_H wikiPageExternalLink NBK1367.
- Factor_H wikiPageExternalLink NBK1425.
- Factor_H wikiPageExternalLink 277400,120700,120920,134370,134371,138470,188040,217030,235400,605336,605337,612922,612923,612924,612925,612926,120700,120920,134370,134371,138470,188040,217030,235400,605336,605337,612922,612923,612924,612925,612926.
- Factor_H wikiPageID "10036477".
- Factor_H wikiPageRevisionID "605319735".
- Factor_H hasPhotoCollection Factor_H.
- Factor_H subject Category:Complement_system.
- Factor_H type Biomolecule.
- Factor_H type Protein.
- Factor_H type BiologicalObject.
- Factor_H comment "Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at typical concentrations of 200–300 micrograms per milliliter). Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue.".
- Factor_H label "Czynnik H".
- Factor_H label "Factor H".
- Factor_H sameAs Faktor_komplemen_H.
- Factor_H sameAs Czynnik_H.
- Factor_H sameAs m.02p_m7c.
- Factor_H sameAs Q581194.
- Factor_H sameAs Q581194.
- Factor_H sameAs HF1.
- Factor_H sameAs 3095.
- Factor_H sameAs 3346.
- Factor_H wasDerivedFrom Factor_H?oldid=605319735.
- Factor_H depiction Model_of_factorH-C3b_complex.png.
- Factor_H isPrimaryTopicOf Factor_H.