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- Farnesyltransferase abstract "Farnesyltransferase (EC 2.5.1.58) is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four-amino acid sequence at the carboxyl terminus of a protein. Farnesyltransferase's targets include members of the Ras superfamily of small GTP-binding proteins critical to cell cycle progression. For this reason, several FTase inhibitors are undergoing testing as anti-cancer agents. FTase inhibitors have shown efficacy as anti-parasitic agents, as well. FTase is also believed to play an important role in development of progeria and various forms of cancers.Farnesyltransferase catalyzes the chemical reactionfarnesyl diphosphate + protein-cysteine S-farnesyl protein + diphosphateThus, the two substrates of this enzyme are farnesyl diphosphate and protein-cysteine, whereas its two products are S-farnesyl protein and diphosphate.".
- Farnesyltransferase ecNumber "2.5.1.58".
- Farnesyltransferase wikiPageExternalLink uonc-nus082905.php.
- Farnesyltransferase wikiPageExternalLink farnesyltransferase-inhibitor-in-cancer-treatment.
- Farnesyltransferase wikiPageID "2581004".
- Farnesyltransferase wikiPageRevisionID "606316238".
- Farnesyltransferase casNumber "131384".
- Farnesyltransferase ecNumber "2.5".
- Farnesyltransferase goCode "4660".
- Farnesyltransferase hasPhotoCollection Farnesyltransferase.
- Farnesyltransferase iubmbEcNumber "2".
- Farnesyltransferase name "Protein farnesyltransferase".
- Farnesyltransferase subject Category:EC_2.5.1.
- Farnesyltransferase type Abstraction100002137.
- Farnesyltransferase type Activator114723079.
- Farnesyltransferase type Catalyst114723628.
- Farnesyltransferase type Chemical114806838.
- Farnesyltransferase type Compound114818238.
- Farnesyltransferase type Enzyme114732946.
- Farnesyltransferase type Enzymes.
- Farnesyltransferase type Macromolecule114944888.
- Farnesyltransferase type Material114580897.
- Farnesyltransferase type Matter100020827.
- Farnesyltransferase type Molecule114682133.
- Farnesyltransferase type OrganicCompound114727670.
- Farnesyltransferase type Part113809207.
- Farnesyltransferase type PhysicalEntity100001930.
- Farnesyltransferase type Protein114728724.
- Farnesyltransferase type Relation100031921.
- Farnesyltransferase type Substance100019613.
- Farnesyltransferase type Thing100002452.
- Farnesyltransferase type Unit109465459.
- Farnesyltransferase type Biomolecule.
- Farnesyltransferase type Enzyme.
- Farnesyltransferase type BiologicalObject.
- Farnesyltransferase comment "Farnesyltransferase (EC 2.5.1.58) is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four-amino acid sequence at the carboxyl terminus of a protein. Farnesyltransferase's targets include members of the Ras superfamily of small GTP-binding proteins critical to cell cycle progression. For this reason, several FTase inhibitors are undergoing testing as anti-cancer agents.".
- Farnesyltransferase label "Farnesiltransferase".
- Farnesyltransferase label "Farnesyltransferase".
- Farnesyltransferase label "Farnesyltransferase".
- Farnesyltransferase label "法尼基轉移酶".
- Farnesyltransferase sameAs Farnesyltransferase.
- Farnesyltransferase sameAs Farnesiltransferase.
- Farnesyltransferase sameAs m.07pg7g.
- Farnesyltransferase sameAs Q410994.
- Farnesyltransferase sameAs Q410994.
- Farnesyltransferase sameAs Farnesyltransferase.
- Farnesyltransferase wasDerivedFrom Farnesyltransferase?oldid=606316238.
- Farnesyltransferase isPrimaryTopicOf Farnesyltransferase.
- Farnesyltransferase name "Protein farnesyltransferase".