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- Flow-FISH abstract "Flow-FISH (fluorescent in-situ hybridization) is a cytogenetic technique to quantify the copy number of specific repetitive elements in genomic DNA of whole cell populations via the combination of flow cytometry with cytogenetic fluorescent in situ hybridization staining protocols. Flow-FISH is most commonly used to quantify the length of telomeres, which are stretches of repetitious DNA (hexameric TTAGGG repeats) at the distal ends of chromosomes in human white blood cells, and a semi-automated method for doing so was recently published in Nature Protocols. Telomere length in white blood cells has been a subject of interest because telomere length in these cell types (and also of other somatic tissues) declines gradually over the human lifespan, resulting in cell senescence, apoptosis, or transformation. This decline has been shown to be a surrogate marker for the concomitant decline in the telomere length of the hematopoietic stem cell pool, with the granulocyte lineage giving the best indication, presumably due to the absence of a long lived memory subtype and comparatively rapid turnover of these cells.".
- Flow-FISH thumbnail Flow-FISH_1.JPG?width=300.
- Flow-FISH wikiPageExternalLink Protocols.htm.
- Flow-FISH wikiPageExternalLink www.flintbox.com.
- Flow-FISH wikiPageExternalLink B23.
- Flow-FISH wikiPageID "15272708".
- Flow-FISH wikiPageRevisionID "526563510".
- Flow-FISH hasPhotoCollection Flow-FISH.
- Flow-FISH subject Category:Biochemistry_methods.
- Flow-FISH subject Category:Flow_cytometry.
- Flow-FISH subject Category:Telomeres.
- Flow-FISH type Ability105616246.
- Flow-FISH type Abstraction100002137.
- Flow-FISH type BiochemistryMethods.
- Flow-FISH type Cognition100023271.
- Flow-FISH type Know-how105616786.
- Flow-FISH type Method105660268.
- Flow-FISH type PsychologicalFeature100023100.
- Flow-FISH comment "Flow-FISH (fluorescent in-situ hybridization) is a cytogenetic technique to quantify the copy number of specific repetitive elements in genomic DNA of whole cell populations via the combination of flow cytometry with cytogenetic fluorescent in situ hybridization staining protocols.".
- Flow-FISH label "Flow-FISH".
- Flow-FISH sameAs m.03hns26.
- Flow-FISH sameAs Q5462042.
- Flow-FISH sameAs Q5462042.
- Flow-FISH sameAs Flow-FISH.
- Flow-FISH wasDerivedFrom Flow-FISH?oldid=526563510.
- Flow-FISH depiction Flow-FISH_1.JPG.
- Flow-FISH isPrimaryTopicOf Flow-FISH.
