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- GOLLD_RNA_motif abstract "Giant, Ornate, Lake- and Lactobacillales-Derived (GOLLD) RNA is a conserved RNA structure present in bacteria. GOLLD RNAs were originally detected based on metagenome sequences of DNA isolated from Lake Gatun in Panama. However, they are known to be present in at least eight strains of cultivated bacteria. GOLLD RNAs are extraordinarily large compared to other RNAs with a conserved, complex secondary structure, and average roughly 800 nucleotides. Such large, complex RNAs are often ribozymes, although the biochemical function of GOLLD RNAs remains unknown. The discovery of large RNAs like GOLLD RNAs among bacteria that are mostly uncultivated under laboratory conditions suggests that many other unusually large RNAs might be found in bacteria that have not yet been studied.The GOLLD RNA in Lactobacillus brevis ATCC 367 was studied experimentally. This GOLLD RNA is apparently encoded by a prophage, and its transcription is increased during the phage lytic cycle. Therefore, this GOLLD RNA presumably serves a function that is useful to the phage during this process. GOLLD RNAs are often located near transfer RNAs (tRNAs), and in some cases a tRNA is predicted to be inside the GOLLD RNA structure itself. However, the biological reason underlying this association is not understood.The Rfam model of GOLLD RNA uses only the 3' half of GOLLD, as this region of the full RNA is highly consistent in its structure.".
- GOLLD_RNA_motif wikiPageID "25311492".
- GOLLD_RNA_motif wikiPageRevisionID "591489633".
- GOLLD_RNA_motif hasPhotoCollection GOLLD_RNA_motif.
- GOLLD_RNA_motif subject Category:Non-coding_RNA.
- GOLLD_RNA_motif comment "Giant, Ornate, Lake- and Lactobacillales-Derived (GOLLD) RNA is a conserved RNA structure present in bacteria. GOLLD RNAs were originally detected based on metagenome sequences of DNA isolated from Lake Gatun in Panama. However, they are known to be present in at least eight strains of cultivated bacteria. GOLLD RNAs are extraordinarily large compared to other RNAs with a conserved, complex secondary structure, and average roughly 800 nucleotides.".
- GOLLD_RNA_motif label "GOLLD RNA motif".
- GOLLD_RNA_motif sameAs m.09gprfr.
- GOLLD_RNA_motif sameAs Q5514070.
- GOLLD_RNA_motif sameAs Q5514070.
- GOLLD_RNA_motif wasDerivedFrom GOLLD_RNA_motif?oldid=591489633.
- GOLLD_RNA_motif isPrimaryTopicOf GOLLD_RNA_motif.