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- GPR44 abstract "G protein-coupled receptor 44 (GPR44) is a human protein. GPR44 has also been designated as CD294 (cluster of differentiation 294).G protein-coupled receptors (GPCRs), such as GPR44, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM]GPR44 has recently been found to belong to the prostanoid receptor family and named DP2, with this becoming the official IUPHAR nomenclature.GPR44 has recently been found when activated by elevated level of prostaglandin D2 (PGD2), it could inhibit hair growth. This suggests the PGD2-GPR44 pathway as a potential target for bald treatment. A particularly promising compound for blocking the PGD2-GPR44 pathway is a compound known as TM-30089, which exhibits a "functional insurmountability" of PGD2 expression.".
- GPR44 entrezgene "11251".
- GPR44 wikiPageExternalLink ReceptorDisplayForward?receptorID=3051.
- GPR44 wikiPageID "14429376".
- GPR44 wikiPageRevisionID "545047034".
- GPR44 hasPhotoCollection GPR44.
- GPR44 requireManualInspection "no".
- GPR44 summaryText "G protein-coupled receptors , such as GPR44, are integral membrane proteins containing 7 putative transmembrane domains . These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM]".
- GPR44 updateCitations "yes".
- GPR44 updatePage "yes".
- GPR44 updateProteinBox "yes".
- GPR44 updateSummary "yes".
- GPR44 subject Category:Clusters_of_differentiation.
- GPR44 subject Category:G_protein_coupled_receptors.
- GPR44 type Biomolecule.
- GPR44 type Protein.
- GPR44 type BiologicalObject.
- GPR44 comment "G protein-coupled receptor 44 (GPR44) is a human protein. GPR44 has also been designated as CD294 (cluster of differentiation 294).G protein-coupled receptors (GPCRs), such as GPR44, are integral membrane proteins containing 7 putative transmembrane domains (TMs).".
- GPR44 label "GPR44".
- GPR44 sameAs m.03d380b.
- GPR44 sameAs Q5514271.
- GPR44 sameAs Q5514271.
- GPR44 wasDerivedFrom GPR44?oldid=545047034.
- GPR44 isPrimaryTopicOf GPR44.