Matches in DBpedia 2014 for { <http://dbpedia.org/resource/GRLF1> ?p ?o. }
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- GRLF1 abstract "Glucocorticoid receptor DNA-binding factor 1 is a protein that in humans is encoded by the GRLF1 gene.The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.".
- GRLF1 entrezgene "2909".
- GRLF1 wikiPageExternalLink report.cgi?report=orth_overview&orth_acc=co00002004.
- GRLF1 wikiPageExternalLink index.shtml.
- GRLF1 wikiPageID "14880271".
- GRLF1 wikiPageRevisionID "591519351".
- GRLF1 hasPhotoCollection GRLF1.
- GRLF1 requireManualInspection "no".
- GRLF1 summaryText "The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene , is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.".
- GRLF1 updateCitations "yes".
- GRLF1 updatePage "yes".
- GRLF1 updateProteinBox "yes".
- GRLF1 updateSummary "yes".
- GRLF1 subject Category:Transcription_factors.
- GRLF1 type Biomolecule.
- GRLF1 type Protein.
- GRLF1 type BiologicalObject.
- GRLF1 comment "Glucocorticoid receptor DNA-binding factor 1 is a protein that in humans is encoded by the GRLF1 gene.The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription.".
- GRLF1 label "GRLF1".
- GRLF1 sameAs m.03h04x1.
- GRLF1 sameAs Q5514484.
- GRLF1 sameAs Q5514484.
- GRLF1 wasDerivedFrom GRLF1?oldid=591519351.
- GRLF1 isPrimaryTopicOf GRLF1.