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- Gastric_mucosa abstract "The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits. In humans it is about 1 mm thick and its surface is smooth, soft, and velvety. It consists of epithelium, lamina propria, and the muscularis mucosae.In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the organ it is thrown into numerous plaits or rugae, which, for the most part, have a longitudinal direction, and are most marked toward the pyloric end of the stomach, and along the greater curvature. These folds are entirely obliterated when the organ becomes distended.When examined with a lens, the inner surface of the mucous membrane presents a peculiar honeycomb appearance from being covered with funnel-like depressions or foveolae of a polygonal or hexagonal form, which vary from 0.12 to 0.25 mm. in diameter. These are the ducts of the gastric glands, and at the bottom of each may be seen one or more minute orifices, the openings of the gland tubes. Gastric glands are simple or branched tubular glands that emerge on the deeper part of the gastric foveola, inside the gastric areas and outlined by the folds of the mucosa. There are three types of glands: cardiac glands (in the proximal part of the stomach), fundic (oxyntic) glands (the dominating type of gland), and pyloric glands.The cardiac glands mainly contain mucus-producing cells called foveolar cells.The bottom part of the oxyntic glands is dominated by zymogenic (chief) cells that produce pepsinogen (an inactive precursor of the pepsin enzyme). Parietal cells, which secrete hydrochloric acid (HCl) are scattered in the glands, with most of them in the middle part. The upper part of the glands consist of mucous neck cells; in this part the dividing cells are seen. The pyloric glands contain mucus-secreting cells.Several types of endocrine cells are found in throughout the gastric mucosa. The pyloric glands contain gastrin-producing cells (G cells); this hormone stimulates acid production from the parietal cells. Enterochromaffin-like cells (ECLs), found in the oxyntic glands release histamine, which also is a powerful stimulant of the acid secretion.The A cells produce glucagon, which mobilizes the hepatic glycogen, and the enterochromaffin cells produce serotonin, which stimulates the contraction of the smooth muscles. The surface of the mucous membrane is covered by a single layer of columnar epithelium. This epithelium commences very abruptly at the cardiac orifice, where there is a sudden transition from the stratified epithelium of the esophagus. The epithelial lining of the gland ducts is of the same character and is continuous with the general epithelial lining of the stomach. An important iodine concentration by sodium-iodide symporter (NIS) is present in mucinous cells of surface epithelium and gastric pits of the fundus and pyloric part of the stomach.".
- Gastric_mucosa dorlandsPrefix "t_22".
- Gastric_mucosa dorlandsSuffix "12831946".
- Gastric_mucosa grayPage "1166".
- Gastric_mucosa graySubject "247".
- Gastric_mucosa thumbnail Illu_stomach2.jpg?width=300.
- Gastric_mucosa wikiPageExternalLink a.6.92.1.1.htm.
- Gastric_mucosa wikiPageExternalLink micview.htm.
- Gastric_mucosa wikiPageID "8235380".
- Gastric_mucosa wikiPageRevisionID "603127377".
- Gastric_mucosa caption "Section of mucous membrane of human stomach, near the cardiac orifice. X 45. c. Cardiac glands. d. Their ducts. cr. Gland similar to the intestinal glands, with goblet cells. mm. Mucous membrane. m. Muscularis mucosæ. m’. Muscular tissue within the mucous membrane.".
- Gastric_mucosa caption "Stomach".
- Gastric_mucosa dorlandspre "t_22".
- Gastric_mucosa dorlandssuf "12831946".
- Gastric_mucosa graypage "1166".
- Gastric_mucosa graysubject "247".
- Gastric_mucosa hasPhotoCollection Gastric_mucosa.
- Gastric_mucosa image "Gray1053.png".
- Gastric_mucosa latin "tunica mucosa gastris".
- Gastric_mucosa name "Gastric mucosa".
- Gastric_mucosa wordnet_type synset-human_body-noun-1.
- Gastric_mucosa subject Category:Stomach.
- Gastric_mucosa type Abstraction100002137.
- Gastric_mucosa type Anatomy106057539.
- Gastric_mucosa type Biology106037666.
- Gastric_mucosa type Cognition100023271.
- Gastric_mucosa type Content105809192.
- Gastric_mucosa type Discipline105996646.
- Gastric_mucosa type KnowledgeDomain105999266.
- Gastric_mucosa type LifeScience106037298.
- Gastric_mucosa type Morphology106078327.
- Gastric_mucosa type NaturalScience106000400.
- Gastric_mucosa type PsychologicalFeature100023100.
- Gastric_mucosa type Science105999797.
- Gastric_mucosa type AnatomicalStructure.
- Gastric_mucosa type AnimalBodyPart.
- Gastric_mucosa type BiologicalObject.
- Gastric_mucosa comment "The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits. In humans it is about 1 mm thick and its surface is smooth, soft, and velvety. It consists of epithelium, lamina propria, and the muscularis mucosae.In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked.".
- Gastric_mucosa label "Gastric mucosa".
- Gastric_mucosa label "Maagslijmvlies".
- Gastric_mucosa label "Magenschleimhaut".
- Gastric_mucosa label "胃粘膜".
- Gastric_mucosa sameAs Magenschleimhaut.
- Gastric_mucosa sameAs 胃粘膜.
- Gastric_mucosa sameAs Maagslijmvlies.
- Gastric_mucosa sameAs m.026x6ht.
- Gastric_mucosa sameAs Q383249.
- Gastric_mucosa sameAs Q383249.
- Gastric_mucosa sameAs Gastric_mucosa.
- Gastric_mucosa wasDerivedFrom Gastric_mucosa?oldid=603127377.
- Gastric_mucosa depiction Illu_stomach2.jpg.
- Gastric_mucosa isPrimaryTopicOf Gastric_mucosa.
- Gastric_mucosa name "Gastric mucosa".