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- Glutamine_synthetase abstract "Glutamine synthetase (GS) (EC 6.3.1.2) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine:Glutamate + ATP + NH3 → Glutamine + ADP + phosphate Glutamine Synthetase uses ammonia produced by nitrate reduction, amino acid degradation, and photorespiration. The amide group of glutamate is a nitrogen source for the synthesis of glutamine pathway metabolites.Other reactions may take place via GS. Competition between ammonium ion and water, their binding affinities, and the concentration of ammonium ion, influences glutamine synthesis and glutamine hydrolysis. Glutamine is formed if an ammonium ion attacks the acyl-phosphate intermediate, while glutamate is remade if water attacks the intermediate. Ammonium ion binds more strongly than water to GS due to electrostatic forces between a cation and a negatively charged pocket. Another possible reaction is upon NH2OH binding to GS, rather than NH4+, yields γ-glutamylhydroxamate.".
- Glutamine_synthetase ecNumber "6.3.1.2".
- Glutamine_synthetase thumbnail MN_MN_ADP_PPQ.png?width=300.
- Glutamine_synthetase wikiPageExternalLink pdb30_1.html.
- Glutamine_synthetase wikiPageExternalLink DisplayIproEntry?ac=IPR008147.
- Glutamine_synthetase wikiPageExternalLink pdb30_1.html.
- Glutamine_synthetase wikiPageID "2599674".
- Glutamine_synthetase wikiPageRevisionID "606316984".
- Glutamine_synthetase altsymbols "GLNS".
- Glutamine_synthetase arm "q".
- Glutamine_synthetase band "31".
- Glutamine_synthetase caption "12".
- Glutamine_synthetase caption "Active site between two monomers of glutamine synthetase from Salmonella typhimurium. Cation binding sites are yellow and orange; ADP is pink; phosphinothricin is blue.".
- Glutamine_synthetase caption "Crystallographic structure of glutamine synthetase from salmonella typhimurium.".
- Glutamine_synthetase casNumber "9023".
- Glutamine_synthetase chromosome "1".
- Glutamine_synthetase ecNumber "6.3".
- Glutamine_synthetase ecnumber "6.3".
- Glutamine_synthetase entrezgene "2752".
- Glutamine_synthetase goCode "4356".
- Glutamine_synthetase hasPhotoCollection Glutamine_synthetase.
- Glutamine_synthetase hgncid "4341".
- Glutamine_synthetase interpro "IPR008146".
- Glutamine_synthetase interpro "IPR008147".
- Glutamine_synthetase iubmbEcNumber "6".
- Glutamine_synthetase name "Glutamine synthetase,".
- Glutamine_synthetase name "beta-Grasp domain".
- Glutamine_synthetase name "catalytic domain".
- Glutamine_synthetase name "glutamate-ammonia ligase".
- Glutamine_synthetase name "glutamate—ammonia ligase".
- Glutamine_synthetase omim "138290".
- Glutamine_synthetase pdb ", , , , , , , ,".
- Glutamine_synthetase pdb "2".
- Glutamine_synthetase pfam "PF00120".
- Glutamine_synthetase pfam "PF03951".
- Glutamine_synthetase pfamClan "CL0286".
- Glutamine_synthetase prosite "PDOC00162".
- Glutamine_synthetase refseq "NM_002065".
- Glutamine_synthetase scop "2".
- Glutamine_synthetase symbol "GLUL".
- Glutamine_synthetase symbol "Gln-synt_C".
- Glutamine_synthetase symbol "Gln-synt_N".
- Glutamine_synthetase uniprot "P15104".
- Glutamine_synthetase width "150".
- Glutamine_synthetase subject Category:EC_6.3.1.
- Glutamine_synthetase type Biomolecule.
- Glutamine_synthetase type Enzyme.
- Glutamine_synthetase type ProteinMolecule.
- Glutamine_synthetase type BiologicalObject.
- Glutamine_synthetase comment "Glutamine synthetase (GS) (EC 6.3.1.2) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine:Glutamate + ATP + NH3 → Glutamine + ADP + phosphate Glutamine Synthetase uses ammonia produced by nitrate reduction, amino acid degradation, and photorespiration. The amide group of glutamate is a nitrogen source for the synthesis of glutamine pathway metabolites.Other reactions may take place via GS.".
- Glutamine_synthetase label "Glutamat-Ammonium-Ligase".
- Glutamine_synthetase label "Glutamina sintetasa".
- Glutamine_synthetase label "Glutamine synthetase".
- Glutamine_synthetase label "Glutamine synthétase".
- Glutamine_synthetase label "谷氨酰胺合成酶".
- Glutamine_synthetase sameAs Glutamat-Ammonium-Ligase.
- Glutamine_synthetase sameAs Glutamina_sintetasa.
- Glutamine_synthetase sameAs Glutamine_synthétase.
- Glutamine_synthetase sameAs m.07qtwt.
- Glutamine_synthetase sameAs Q418306.
- Glutamine_synthetase sameAs Q418306.
- Glutamine_synthetase sameAs 2.
- Glutamine_synthetase sameAs 3426.
- Glutamine_synthetase sameAs 3987.
- Glutamine_synthetase wasDerivedFrom Glutamine_synthetase?oldid=606316984.
- Glutamine_synthetase depiction MN_MN_ADP_PPQ.png.
- Glutamine_synthetase isPrimaryTopicOf Glutamine_synthetase.
- Glutamine_synthetase name "glutamate—ammonia ligase".
