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- Glymphatic_system abstract "The glymphatic system (or glymphatic clearance pathway) is a functional waste clearance pathway for the mammalian central nervous system (CNS). Although the lymphatic system is responsible for removing extracellular proteins, excess fluid, and metabolic waste products from peripheral tissues, curiously, the brain and spinal cord lack a lymphatic vasculature. Glymphatic flow answers the long standing question of how the sensitive neural tissue of the CNS functions in the absence of a conventional lymphatic circulation. The pathway consists of a para-arterial influx route for cerebrospinal fluid (CSF) to enter the brain parenchyma, coupled to a clearance mechanism for the removal of interstitial fluid (ISF) and extracellular solutes from the interstitial compartments of the brain and spinal cord. Exchange of solutes between the CSF and the ISF is driven by arterial pulsation and regulated during sleep by the expansion and contraction of brain extracellular space. Clearance of soluble proteins, waste products, and excess extracellular fluid is accomplished through convective bulk flow of the ISF, facilitated by astrocytic aquaporin 4 (AQP4) water channels.The glymphatic system was coined by the Danish neuroscientist Maiken Nedergaard in recognition of its dependence upon glial cells and its performance of peripheral 'lymphatic' functions in the CNS.".
- Glymphatic_system wikiPageExternalLink goodnight-sleep-clean.html.
- Glymphatic_system wikiPageID "37185825".
- Glymphatic_system wikiPageRevisionID "606036423".
- Glymphatic_system caption "Astrocytes stained for GFAP and aquaporin-4".
- Glymphatic_system caption "Mammalian glymphatic system".
- Glymphatic_system hasPhotoCollection Glymphatic_system.
- Glymphatic_system name "Glymphatic System".
- Glymphatic_system width "300".
- Glymphatic_system subject Category:Central_nervous_system.
- Glymphatic_system subject Category:Lymphatic_system.
- Glymphatic_system type AnatomicalStructure.
- Glymphatic_system type BiologicalObject.
- Glymphatic_system comment "The glymphatic system (or glymphatic clearance pathway) is a functional waste clearance pathway for the mammalian central nervous system (CNS). Although the lymphatic system is responsible for removing extracellular proteins, excess fluid, and metabolic waste products from peripheral tissues, curiously, the brain and spinal cord lack a lymphatic vasculature.".
- Glymphatic_system label "Glymphatic system".
- Glymphatic_system label "Układ glimfatyczny".
- Glymphatic_system sameAs Układ_glimfatyczny.
- Glymphatic_system sameAs m.0n5wqql.
- Glymphatic_system sameAs Q15474254.
- Glymphatic_system sameAs Q15474254.
- Glymphatic_system wasDerivedFrom Glymphatic_system?oldid=606036423.
- Glymphatic_system isPrimaryTopicOf Glymphatic_system.
- Glymphatic_system name "Glymphatic System".