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- Gnotobiotic_animal abstract "A gnotobiotic animal (from Greek roots gnostos 'known' and bios 'life') is an animal in which only certain known strains of bacteria and other microorganisms are present. Technically, the term also includes germ-free animals, as the status of their microbial communities is also known. However, the term gnotobiotic is often incorrectly contrasted with germ-free.Gnotobiotic animals (also 'gnotobiotes' or 'gnotobionts') are born in aseptic conditions, which may include removal from the mother by Caesarean section and immediate transfer of the newborn to an isolator where all incoming air, food and water is sterilized. Such animals are normally reared in a sterile or microbially-controlled laboratory environment, and they are only exposed to those microorganisms that the researchers wish to have present in the animal. These gnotobionts are used to study the symbiotic relationships between an animal and one or more of the microorganisms that may inhabit its body. This technique is important for microbiologists because it allows them to study only a select few symbiotic interactions at a time (see Scientific control), whereas animals that develop under normal conditions may quickly acquire a microbiota that includes hundreds or thousands of unique organisms.Animals reared in a gnotobiotic colony often have poorly developed immune systems, lower cardiac output, thin intestinal walls and high susceptibility to infectious pathogens.A recent study done on gnotobiotic mice described a method in which certain strains of gut bacteria were found to transmit a particular phenotype to recipient germ-free mice. This approach enables a systems-level understanding of microbial contributions to human biology.Such animals may also be used in animal production, especially in the rearing of pigs. After the Caesarean birth, these animals are introduced to their natural microflora in a stepwise fashion. This avoids undesired infections and leads to faster growth.".
- Gnotobiotic_animal wikiPageID "6002272".
- Gnotobiotic_animal wikiPageRevisionID "599563242".
- Gnotobiotic_animal hasPhotoCollection Gnotobiotic_animal.
- Gnotobiotic_animal subject Category:Model_organisms.
- Gnotobiotic_animal type LivingThing100004258.
- Gnotobiotic_animal type ModelOrganisms.
- Gnotobiotic_animal type Object100002684.
- Gnotobiotic_animal type Organism100004475.
- Gnotobiotic_animal type PhysicalEntity100001930.
- Gnotobiotic_animal type Whole100003553.
- Gnotobiotic_animal comment "A gnotobiotic animal (from Greek roots gnostos 'known' and bios 'life') is an animal in which only certain known strains of bacteria and other microorganisms are present. Technically, the term also includes germ-free animals, as the status of their microbial communities is also known.".
- Gnotobiotic_animal label "Gnotobiote".
- Gnotobiotic_animal label "Gnotobiotic animal".
- Gnotobiotic_animal label "ノトバイオート".
- Gnotobiotic_animal sameAs Gnotobiote.
- Gnotobiotic_animal sameAs ノトバイオート.
- Gnotobiotic_animal sameAs m.0fk2c3.
- Gnotobiotic_animal sameAs Q3109501.
- Gnotobiotic_animal sameAs Q3109501.
- Gnotobiotic_animal sameAs Gnotobiotic_animal.
- Gnotobiotic_animal wasDerivedFrom Gnotobiotic_animal?oldid=599563242.
- Gnotobiotic_animal isPrimaryTopicOf Gnotobiotic_animal.