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- Granzyme_B abstract "Granzyme B is a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs), natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells.Granzyme B has also more recently found to be produced by a wide range of non-cytotoxic cells ranging from basophils and mast cells to smooth muscle cells. The secondary functions of granzyme B are also numerous. Granzyme B has shown to be involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodelling.Elevated levels of granzyme B are also implicated in a number of autoimmune diseases, several skin diseases, and type 1 diabetes.".
- Granzyme_B ecNumber "3.4.21.79".
- Granzyme_B wikiPageID "1602856".
- Granzyme_B wikiPageRevisionID "604398755".
- Granzyme_B casNumber "143180".
- Granzyme_B ecNumber "3.4".
- Granzyme_B iubmbEcNumber "3".
- Granzyme_B name "Granzyme B".
- Granzyme_B subject Category:EC_3.4.21.
- Granzyme_B type Biomolecule.
- Granzyme_B type Enzyme.
- Granzyme_B type BiologicalObject.
- Granzyme_B comment "Granzyme B is a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs), natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells.Granzyme B has also more recently found to be produced by a wide range of non-cytotoxic cells ranging from basophils and mast cells to smooth muscle cells. The secondary functions of granzyme B are also numerous.".
- Granzyme_B label "Granzyme B".
- Granzyme_B sameAs m.0t_cv4_.
- Granzyme_B sameAs Q12646460.
- Granzyme_B sameAs Q12646460.
- Granzyme_B wasDerivedFrom Granzyme_B?oldid=604398755.
- Granzyme_B isPrimaryTopicOf Granzyme_B.
- Granzyme_B name "Granzyme B".