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- Group_II_intron abstract "Group II introns are a large class of self-catalytic ribozymes as well as mobile genetic element found within the genes of all three domains of life. Ribozyme activity (e.g., Self-splicing) can occur under high-salt conditions in vitro. However, assistance from proteins is required for in vivo splicing. In contrast to group I introns, intron excision occurs in the absence of GTP and involves the formation of a lariat, with an A-residue branchpoint strongly resembling that found in lariats formed during splicing of nuclear pre-mRNA. It is hypothesized that pre-mRNA splicing (see spliceosome) may have evolved from group II introns due to the similar catalytic mechanism as well the structural similarity of the Domain V substructure to the U6/U2 extended snRNA. Finally, their ability to site-specifically mobilize to new DNA sites has been exploited as a tool for biotechnology.".
- Group_II_intron thumbnail IntronGroupII.jpg?width=300.
- Group_II_intron wikiPageID "7916185".
- Group_II_intron wikiPageRevisionID "591520827".
- Group_II_intron hasPhotoCollection Group_II_intron.
- Group_II_intron id "RF00029".
- Group_II_intron name "Group II catalytic intron".
- Group_II_intron subject Category:RNA.
- Group_II_intron subject Category:RNA_splicing.
- Group_II_intron subject Category:Ribozymes.
- Group_II_intron comment "Group II introns are a large class of self-catalytic ribozymes as well as mobile genetic element found within the genes of all three domains of life. Ribozyme activity (e.g., Self-splicing) can occur under high-salt conditions in vitro. However, assistance from proteins is required for in vivo splicing.".
- Group_II_intron label "Group II intron".
- Group_II_intron sameAs m.026jyf1.
- Group_II_intron sameAs Q5611160.
- Group_II_intron sameAs Q5611160.
- Group_II_intron wasDerivedFrom Group_II_intron?oldid=591520827.
- Group_II_intron depiction IntronGroupII.jpg.
- Group_II_intron isPrimaryTopicOf Group_II_intron.
