Matches in DBpedia 2014 for { <http://dbpedia.org/resource/HEXB> ?p ?o. }
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- HEXB abstract "Beta-hexosaminidase subunit beta is an enzyme that in humans is encoded by the HEXB gene.Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II).".
- HEXB entrezgene "3074".
- HEXB wikiPageID "5880893".
- HEXB wikiPageRevisionID "595368944".
- HEXB hasPhotoCollection HEXB.
- HEXB requireManualInspection "no".
- HEXB summaryText "Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease .".
- HEXB updateCitations "yes".
- HEXB updatePage "yes".
- HEXB updateProteinBox "yes".
- HEXB updateSummary "yes".
- HEXB type Biomolecule.
- HEXB type Protein.
- HEXB type BiologicalObject.
- HEXB comment "Beta-hexosaminidase subunit beta is an enzyme that in humans is encoded by the HEXB gene.Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes.".
- HEXB label "HEXB".
- HEXB sameAs m.03gq7kq.
- HEXB sameAs Q5629497.
- HEXB sameAs Q5629497.
- HEXB sameAs HEXB.
- HEXB sameAs 2033.
- HEXB wasDerivedFrom HEXB?oldid=595368944.
- HEXB isPrimaryTopicOf HEXB.