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- Heavy_chain abstract "A heavy chain is the large polypeptide subunit of a protein complex, such as a motor protein (e.g. myosin, kinesin, or dynein) or antibody (or immunoglobulin). It commonly refers to the immunoglobulin heavy chain. The heavy (H) chain is the larger of the two types of chains that comprise a normal immunoglobulin or antibody molecule. The heavy chain portion of an antibody contains 2 regions; the Fab (Antigen-binding portion) and Fc (Constant region; confers biological activity such as phagocytosis of microorganisms, lysis, and clumping of organisms together). Amino acid sequence determines the type of heavy chains, and heavy chains define the isotype of Ig. Immunoglobulin G has γ gamma heavy chains, IgA has α alpha heavy chains, IgM has μ mu heavy chains, IgD has δ delta heavy chains, and IgE has ε epsilon heavy chains. In contrast, all light chains are either κ kappa or λ lambda light chains, either of which may be found on any Ig molecule, regardless of isotype. Each Ig unit is made up of 2 heavy chains, 2 light chains, and has 2 antigen-binding sites. Heavy chain is joined with the light chain with the help of disulphide bond.".
- Heavy_chain thumbnail An_Antibody_molecule.jpg?width=300.
- Heavy_chain wikiPageID "21444840".
- Heavy_chain wikiPageRevisionID "570918154".
- Heavy_chain hasPhotoCollection Heavy_chain.
- Heavy_chain subject Category:Protein_complexes.
- Heavy_chain type Abstraction100002137.
- Heavy_chain type Cognition100023271.
- Heavy_chain type Complex105870365.
- Heavy_chain type Concept105835747.
- Heavy_chain type Content105809192.
- Heavy_chain type Idea105833840.
- Heavy_chain type ProteinComplexes.
- Heavy_chain type PsychologicalFeature100023100.
- Heavy_chain type Whole105869584.
- Heavy_chain comment "A heavy chain is the large polypeptide subunit of a protein complex, such as a motor protein (e.g. myosin, kinesin, or dynein) or antibody (or immunoglobulin). It commonly refers to the immunoglobulin heavy chain. The heavy (H) chain is the larger of the two types of chains that comprise a normal immunoglobulin or antibody molecule.".
- Heavy_chain label "Heavy chain".
- Heavy_chain sameAs m.05_5_4z.
- Heavy_chain sameAs Q17037912.
- Heavy_chain sameAs Q17037912.
- Heavy_chain sameAs Heavy_chain.
- Heavy_chain wasDerivedFrom Heavy_chain?oldid=570918154.
- Heavy_chain depiction An_Antibody_molecule.jpg.
- Heavy_chain isPrimaryTopicOf Heavy_chain.
