Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Heparin-binding_EGF-like_growth_factor> ?p ?o. }
Showing items 1 to 35 of
35
with 100 items per page.
- Heparin-binding_EGF-like_growth_factor abstract "Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. An epidermal growth factor produced by monocytes and macrophages, due to an affinity for heparin is termed HB-EGF. It has been shown to play a role in wound healing, cardiac hypertrophy, and heart development and function. First identified in the conditioned media of human macrophage-like cells, HB-EGF is an 87-amino acid glycoprotein that displays highly regulated gene expression. Ectodomain shedding results in the soluble mature form of HB-EGF, which influences the mitogenicity and chemotactic factors for smooth muscle cells and fibroblasts. The transmembrane form of HB-EGF is the unique receptor for diphtheria toxin and functions in juxtacrine signaling in cells. Both forms of HB-EGF participate in normal physiological processes and in pathological processes including tumor progression and metastasis, organ hyperplasia, and atherosclerotic disease. HB-EGF can bind two locations on cell surfaces: heparan sulfate proteoglycans and EGF-receptor effecting cell to cell interactions.".
- Heparin-binding_EGF-like_growth_factor entrezgene "1839".
- Heparin-binding_EGF-like_growth_factor wikiPageID "11883272".
- Heparin-binding_EGF-like_growth_factor wikiPageRevisionID "591631444".
- Heparin-binding_EGF-like_growth_factor hasPhotoCollection Heparin-binding_EGF-like_growth_factor.
- Heparin-binding_EGF-like_growth_factor subject Category:Growth_factors.
- Heparin-binding_EGF-like_growth_factor subject Category:Morphogens.
- Heparin-binding_EGF-like_growth_factor type Abstraction100002137.
- Heparin-binding_EGF-like_growth_factor type Chemical114806838.
- Heparin-binding_EGF-like_growth_factor type Compound114818238.
- Heparin-binding_EGF-like_growth_factor type GrowthFactor114734348.
- Heparin-binding_EGF-like_growth_factor type GrowthFactors.
- Heparin-binding_EGF-like_growth_factor type Macromolecule114944888.
- Heparin-binding_EGF-like_growth_factor type Material114580897.
- Heparin-binding_EGF-like_growth_factor type Matter100020827.
- Heparin-binding_EGF-like_growth_factor type Molecule114682133.
- Heparin-binding_EGF-like_growth_factor type OrganicCompound114727670.
- Heparin-binding_EGF-like_growth_factor type Part113809207.
- Heparin-binding_EGF-like_growth_factor type PhysicalEntity100001930.
- Heparin-binding_EGF-like_growth_factor type Protein114728724.
- Heparin-binding_EGF-like_growth_factor type Relation100031921.
- Heparin-binding_EGF-like_growth_factor type Substance100019613.
- Heparin-binding_EGF-like_growth_factor type Thing100002452.
- Heparin-binding_EGF-like_growth_factor type Unit109465459.
- Heparin-binding_EGF-like_growth_factor type Biomolecule.
- Heparin-binding_EGF-like_growth_factor type Protein.
- Heparin-binding_EGF-like_growth_factor type BiologicalObject.
- Heparin-binding_EGF-like_growth_factor comment "Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. An epidermal growth factor produced by monocytes and macrophages, due to an affinity for heparin is termed HB-EGF. It has been shown to play a role in wound healing, cardiac hypertrophy, and heart development and function.".
- Heparin-binding_EGF-like_growth_factor label "Heparin-binding EGF-like growth factor".
- Heparin-binding_EGF-like_growth_factor sameAs m.02rwp_2.
- Heparin-binding_EGF-like_growth_factor sameAs Q14914534.
- Heparin-binding_EGF-like_growth_factor sameAs Q14914534.
- Heparin-binding_EGF-like_growth_factor sameAs Heparin-binding_EGF-like_growth_factor.
- Heparin-binding_EGF-like_growth_factor wasDerivedFrom Heparin-binding_EGF-like_growth_factor?oldid=591631444.
- Heparin-binding_EGF-like_growth_factor isPrimaryTopicOf Heparin-binding_EGF-like_growth_factor.