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- Heparin_cofactor_II abstract "Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate ("minor antithrombin"). The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.Heparin Cofactor II deficiency can lead to increased thrombin generation and a hypercoagulable state.".
- Heparin_cofactor_II entrezgene "3053".
- Heparin_cofactor_II wikiPageExternalLink merops.cgi?id=I04.019.
- Heparin_cofactor_II wikiPageID "5999650".
- Heparin_cofactor_II wikiPageRevisionID "489685556".
- Heparin_cofactor_II hasPhotoCollection Heparin_cofactor_II.
- Heparin_cofactor_II requireManualInspection "no".
- Heparin_cofactor_II summaryText "The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.".
- Heparin_cofactor_II updateCitations "yes".
- Heparin_cofactor_II updatePage "yes".
- Heparin_cofactor_II updateProteinBox "yes".
- Heparin_cofactor_II updateSummary "yes".
- Heparin_cofactor_II subject Category:Cofactors.
- Heparin_cofactor_II type Abstraction100002137.
- Heparin_cofactor_II type Chemical114806838.
- Heparin_cofactor_II type Cofactor114800706.
- Heparin_cofactor_II type Cofactors.
- Heparin_cofactor_II type Compound114818238.
- Heparin_cofactor_II type Material114580897.
- Heparin_cofactor_II type Matter100020827.
- Heparin_cofactor_II type Part113809207.
- Heparin_cofactor_II type PhysicalEntity100001930.
- Heparin_cofactor_II type Relation100031921.
- Heparin_cofactor_II type Substance100019613.
- Heparin_cofactor_II type Biomolecule.
- Heparin_cofactor_II type Protein.
- Heparin_cofactor_II type BiologicalObject.
- Heparin_cofactor_II comment "Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate ("minor antithrombin"). The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily.".
- Heparin_cofactor_II label "Heparin cofactor II".
- Heparin_cofactor_II sameAs SERPIND1.
- Heparin_cofactor_II sameAs m.0fjym0.
- Heparin_cofactor_II sameAs Q5731649.
- Heparin_cofactor_II sameAs Q5731649.
- Heparin_cofactor_II sameAs SERPIND1.
- Heparin_cofactor_II sameAs 852.
- Heparin_cofactor_II sameAs Heparin_cofactor_II.
- Heparin_cofactor_II wasDerivedFrom Heparin_cofactor_II?oldid=489685556.
- Heparin_cofactor_II isPrimaryTopicOf Heparin_cofactor_II.