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- Hepatitis_C_virus_internal_ribosome_entry_site abstract "Protein translation of most eukaryotic mRNAs requires association of Met-tRNA, several eukaryotic initiation factors, and GTP with the 40S ribosomal subunit. The ribosome can only bind the capped mRNA after binding to the initiator tRNA. Translation of hepatitis C virus (HCV) mRNA is initiated by a different mechanism from the usual 5' cap-binding model. This alternate mechanism relies on the direct binding of the 40S ribosomal subunit by the internal ribosome entry site (IRES) in the 5' UTR of HCV RNA. HCV IRES adopts a complex structure, and may differ significantly from IRES elements identified in picornaviruses. A small number of eukaryotic mRNA have been shown to be translated by internal ribosome entry.".
- Hepatitis_C_virus_internal_ribosome_entry_site thumbnail RF00061.jpg?width=300.
- Hepatitis_C_virus_internal_ribosome_entry_site wikiPageID "11420912".
- Hepatitis_C_virus_internal_ribosome_entry_site wikiPageRevisionID "579110345".
- Hepatitis_C_virus_internal_ribosome_entry_site altsymbols "HCV_IRES".
- Hepatitis_C_virus_internal_ribosome_entry_site caption "Predicted secondary structure and sequence conservation of IRES_HCV".
- Hepatitis_C_virus_internal_ribosome_entry_site hasPhotoCollection Hepatitis_C_virus_internal_ribosome_entry_site.
- Hepatitis_C_virus_internal_ribosome_entry_site id "RF00061".
- Hepatitis_C_virus_internal_ribosome_entry_site name "Hepatitis C virus internal ribosome entry site".
- Hepatitis_C_virus_internal_ribosome_entry_site rfam "RF00061".
- Hepatitis_C_virus_internal_ribosome_entry_site rnaType Cis-regulatory_element.
- Hepatitis_C_virus_internal_ribosome_entry_site rnaType Internal_ribosome_entry_site.
- Hepatitis_C_virus_internal_ribosome_entry_site symbol "IRES_HCV".
- Hepatitis_C_virus_internal_ribosome_entry_site taxDomain "Viruses".
- Hepatitis_C_virus_internal_ribosome_entry_site subject Category:Cis-regulatory_RNA_elements.
- Hepatitis_C_virus_internal_ribosome_entry_site subject Category:Hepatitis_C_virus.
- Hepatitis_C_virus_internal_ribosome_entry_site subject Category:Internal_ribosome_entry_site.
- Hepatitis_C_virus_internal_ribosome_entry_site type Abstraction100002137.
- Hepatitis_C_virus_internal_ribosome_entry_site type Cis-regulatoryRNAElements.
- Hepatitis_C_virus_internal_ribosome_entry_site type Cognition100023271.
- Hepatitis_C_virus_internal_ribosome_entry_site type Component105868954.
- Hepatitis_C_virus_internal_ribosome_entry_site type Concept105835747.
- Hepatitis_C_virus_internal_ribosome_entry_site type Content105809192.
- Hepatitis_C_virus_internal_ribosome_entry_site type Idea105833840.
- Hepatitis_C_virus_internal_ribosome_entry_site type Part105867413.
- Hepatitis_C_virus_internal_ribosome_entry_site type PsychologicalFeature100023100.
- Hepatitis_C_virus_internal_ribosome_entry_site comment "Protein translation of most eukaryotic mRNAs requires association of Met-tRNA, several eukaryotic initiation factors, and GTP with the 40S ribosomal subunit. The ribosome can only bind the capped mRNA after binding to the initiator tRNA. Translation of hepatitis C virus (HCV) mRNA is initiated by a different mechanism from the usual 5' cap-binding model.".
- Hepatitis_C_virus_internal_ribosome_entry_site label "Hepatitis C virus internal ribosome entry site".
- Hepatitis_C_virus_internal_ribosome_entry_site sameAs m.02rby8b.
- Hepatitis_C_virus_internal_ribosome_entry_site sameAs Q5731724.
- Hepatitis_C_virus_internal_ribosome_entry_site sameAs Q5731724.
- Hepatitis_C_virus_internal_ribosome_entry_site sameAs Hepatitis_C_virus_internal_ribosome_entry_site.
- Hepatitis_C_virus_internal_ribosome_entry_site wasDerivedFrom Hepatitis_C_virus_internal_ribosome_entry_site?oldid=579110345.
- Hepatitis_C_virus_internal_ribosome_entry_site depiction RF00061.jpg.
- Hepatitis_C_virus_internal_ribosome_entry_site isPrimaryTopicOf Hepatitis_C_virus_internal_ribosome_entry_site.
