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- Humulin abstract "Humulin is the brand name for a group of biosynthetic human insulin products, developed by Arthur Riggs, working with Genentech in 1978 (Generic names regular insulin, insulin isophane and the Lente series consisting of Lente (known generically as insulin zinc suspension) is actually a mixture of Ultralente and Semilente) and later acquired by Eli Lilly and Company, the company who arguably facilitated the product's approval with the U.S. Food and Drug Administration. The Lente series was discontinued by Lilly in 2005. Prior to the development of synthesized human insulin, patients were dependent on animal insulin which was more costly, less accessible, and caused infections in some patients.Humulin is synthesized in a laboratory strain of Escherichia coli bacteria which has been genetically altered with recombinant DNA to produce biosynthetic human insulin. Humulin R consists of zinc-insulin crystals dissolved in a clear fluid. The synthesized insulin is then combined with other compounds or types of insulin which affect its shelf life and absorption. For example, Humulin N is combined with protamine to extend the time-activity profile of Humulin R for an extended period.Humulin by itself is a short-acting insulin. Humulin R, like many other form of injectable insulin, is intended for subcutaneous injection, so it should not be used intramuscularly, since its dispersion in the rest of the body would take more time.It is currently sold by Eli Lilly under different types: Humulin R (REGULAR human insulin injection [rDNA origin]) is a short-acting insulin that has a relatively short duration of activity as compared with other insulins. Humulin R Regular U-500 (Concentrated) insulin human injection, USP (rDNA Origin) is a stronger concentration (500 units/mL) of Humulin R. Humulin N (human NPH insulin injection [rDNA origin]) is an intermediate-acting insulin with a slower onset of action and a longer duration of activity than Humulin R. Humulin 70/30 (70% human insulin isophane suspension, 30% human insulin injection [rDNA origin]) is a mixture insulin. It is an intermediate-acting insulin combined with the onset of action of Humulin Humulin 50/50 (50% human insulin isophane suspension, 50% human insulin injection [rDNA origin]) is a mixture insulin. It is an intermediate-acting insulin combined with the onset of action of Humulin R.Humulin is identical in chemical structure to human insulin.".
- Humulin wikiPageExternalLink humulin-brand-of-insulins.jsp.
- Humulin wikiPageExternalLink humulin-brand-of-insulins.jsp.
- Humulin wikiPageID "17229593".
- Humulin wikiPageRevisionID "545573333".
- Humulin hasPhotoCollection Humulin.
- Humulin subject Category:Eli_Lilly_and_Company.
- Humulin subject Category:Human_proteins.
- Humulin subject Category:Insulin_therapies.
- Humulin type Abstraction100002137.
- Humulin type Act100030358.
- Humulin type Activity100407535.
- Humulin type Care100654885.
- Humulin type Chemical114806838.
- Humulin type Compound114818238.
- Humulin type Event100029378.
- Humulin type HumanProteins.
- Humulin type InsulinTherapies.
- Humulin type Macromolecule114944888.
- Humulin type Material114580897.
- Humulin type Matter100020827.
- Humulin type MedicalCare100657604.
- Humulin type Molecule114682133.
- Humulin type OrganicCompound114727670.
- Humulin type Part113809207.
- Humulin type PhysicalEntity100001930.
- Humulin type Protein114728724.
- Humulin type PsychologicalFeature100023100.
- Humulin type Relation100031921.
- Humulin type Substance100019613.
- Humulin type Therapy100661091.
- Humulin type Thing100002452.
- Humulin type Treatment100658082.
- Humulin type Unit109465459.
- Humulin type Work100575741.
- Humulin type YagoPermanentlyLocatedEntity.
- Humulin comment "Humulin is the brand name for a group of biosynthetic human insulin products, developed by Arthur Riggs, working with Genentech in 1978 (Generic names regular insulin, insulin isophane and the Lente series consisting of Lente (known generically as insulin zinc suspension) is actually a mixture of Ultralente and Semilente) and later acquired by Eli Lilly and Company, the company who arguably facilitated the product's approval with the U.S. Food and Drug Administration.".
- Humulin label "Humulin".
- Humulin label "Humulina".
- Humulin sameAs Humulina.
- Humulin sameAs m.043kngt.
- Humulin sameAs Q2893248.
- Humulin sameAs Q2893248.
- Humulin sameAs Humulin.
- Humulin wasDerivedFrom Humulin?oldid=545573333.
- Humulin isPrimaryTopicOf Humulin.