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- Hydroxyzine abstract "Hydroxyzine (/haɪˈdrɒksɨziːn/; sold as Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine class. It was first synthesized by Union Chimique Belge in 1956 and was marketed by Pfizer in the United States later the same year, and is still in widespread use today.Due to its antagonistic effects on several receptor systems in the brain, hydroxyzine is claimed to have strong anxiolytic and mild antiobsessive as well as antipsychotic properties. Today it is used primarily for the symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Because of its antihistamine effects it can also be used for the treatment of severe cases of itching, hyperalgesia and motion sickness-induced nausea, it has also been used in some cases to relieve the effects of opioid withdrawal. Even though it is an effective sedative, hypnotic, analgesic, and tranquilizer, it allegedly shares virtually none of the abuse, dependence, addiction, and toxicity potential of other drugs used for the same range of therapeutic reasons.[citation needed]Hydroxyzine has been used in medical practice with opioid analgesics to increase the analgesic efficacy of opioids, and by recreational drug users to maximise the effects of opiates, and/or preempt some side effects of opioids like itching, nausea, and vomiting.Hydroxyzine preparations usually require a doctor's prescription. The drug is available in two formulations, the pamoate and the dihydrochloride or hydrochloride salts. Vistaril, Equipose, Masmoran, and Paxistil are preparations of the pamoate salt, while Atarax, Alamon, Aterax, Durrax, Tran-Q, Orgatrax, Quiess, and Tranquizine are of the hydrochloride salt.Other drugs related to hydroxyzine are cyclizine, buclizine, and meclizine, and they share all or most of the benefits, indications, contraindications, cautions, and side effects of hydroxyzine. The second-generation antihistamine cetirizine is in fact one of the metabolites of hydroxyzine produced in the human body. Unlike hydroxyzine, cetirizine is not reported to appreciably cross the blood-brain barrier, but it has been reported to be associated with dystonic reactions as well as sedation. Therefore it has a narrower spectrum of effects, making it an effective antihistamine but removing some or all of the anxiolytic and analgesic-sparing properties, but it may cause dystonic reactions and drowsiness in some patients.".
- Hydroxyzine atcPrefix "N05".
- Hydroxyzine atcSuffix "BB01".
- Hydroxyzine casNumber "68-88-2".
- Hydroxyzine chEBI "5818".
- Hydroxyzine drugbank "DB00557".
- Hydroxyzine fdaUniiCode "30S50YM8OG".
- Hydroxyzine iupacName "(±)-2-(2-{4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl}ethoxy)ethanol".
- Hydroxyzine pubchem "3658".
- Hydroxyzine thumbnail Hydroxyzine.svg?width=300.
- Hydroxyzine wikiPageExternalLink dpdirect.jsp?name=Hydroxyzine.
- Hydroxyzine wikiPageExternalLink 11795s16.pdf.
- Hydroxyzine wikiPageExternalLink monograph?cid=med&drugid=6144&drugname=Vistaril+Oral&monotype=monograph&print=1.
- Hydroxyzine wikiPageExternalLink uspi_vistaril.pdf.
- Hydroxyzine wikiPageExternalLink hydrox_ids.htm.
- Hydroxyzine wikiPageExternalLink ABSTRACT?SRETRY=0.
- Hydroxyzine wikiPageExternalLink ABSTRACT?CRETRY=1&SRETRY=0.
- Hydroxyzine wikiPageExternalLink ABSTRACT.
- Hydroxyzine wikiPageID "733497".
- Hydroxyzine wikiPageRevisionID "606741525".
- Hydroxyzine atcPrefix "N05".
- Hydroxyzine atcSuffix "BB01".
- Hydroxyzine bioavailability "High in-vivo".
- Hydroxyzine c "21".
- Hydroxyzine casNumber "68".
- Hydroxyzine chebi "5818".
- Hydroxyzine chembl "896".
- Hydroxyzine chemspiderid "3531".
- Hydroxyzine cl "1".
- Hydroxyzine drugbank "DB00557".
- Hydroxyzine eliminationHalfLife "86400.0".
- Hydroxyzine excretion Feces.
- Hydroxyzine excretion Urine.
- Hydroxyzine h "27".
- Hydroxyzine hasPhotoCollection Hydroxyzine.
- Hydroxyzine image "Hydroxyzine-3d-sticks.png".
- Hydroxyzine inchi "1".
- Hydroxyzine inchikey "ZQDWXGKKHFNSQK-UHFFFAOYAL".
- Hydroxyzine iupacName "-2".
- Hydroxyzine kegg "D08054".
- Hydroxyzine legalAu "S4".
- Hydroxyzine legalStatus "Rx-only".
- Hydroxyzine medlineplus "a682866".
- Hydroxyzine metabolism Liver.
- Hydroxyzine molecularWeight "374.904".
- Hydroxyzine n "2".
- Hydroxyzine o "2".
- Hydroxyzine pregnancyAu "A".
- Hydroxyzine pregnancyUs "C".
- Hydroxyzine proteinBound "93.0".
- Hydroxyzine pubchem "3658".
- Hydroxyzine routesOfAdministration Intramuscular_injection.
- Hydroxyzine routesOfAdministration Mouth.
- Hydroxyzine smiles "Clc1cccCN3CCNCCOCCO".
- Hydroxyzine stdinchi "1".
- Hydroxyzine stdinchikey "ZQDWXGKKHFNSQK-UHFFFAOYSA-N".
- Hydroxyzine tradename "Vistaril".
- Hydroxyzine unii "30".
- Hydroxyzine verifiedrevid "461774177".
- Hydroxyzine subject Category:Alcohols.
- Hydroxyzine subject Category:Analgesics.
- Hydroxyzine subject Category:Antiemetics.
- Hydroxyzine subject Category:Anxiolytics.
- Hydroxyzine subject Category:Belgian_inventions.
- Hydroxyzine subject Category:Ethers.
- Hydroxyzine subject Category:H1_receptor_antagonists.
- Hydroxyzine subject Category:Muscarinic_antagonists.
- Hydroxyzine subject Category:Organochlorides.
- Hydroxyzine subject Category:Piperazines.
- Hydroxyzine subject Category:Sedatives.
- Hydroxyzine type Drug.
- Hydroxyzine type DrugProduct.
- Hydroxyzine type FunctionalSubstance.
- Hydroxyzine comment "Hydroxyzine (/haɪˈdrɒksɨziːn/; sold as Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine class. It was first synthesized by Union Chimique Belge in 1956 and was marketed by Pfizer in the United States later the same year, and is still in widespread use today.Due to its antagonistic effects on several receptor systems in the brain, hydroxyzine is claimed to have strong anxiolytic and mild antiobsessive as well as antipsychotic properties.".
- Hydroxyzine label "Hidroxicina".
- Hydroxyzine label "Hidroxizina".
- Hydroxyzine label "Hydroksyzyna".
- Hydroxyzine label "Hydroxyzin".
- Hydroxyzine label "Hydroxyzine".
- Hydroxyzine label "Hydroxyzine".
- Hydroxyzine label "Idroxizina".
- Hydroxyzine label "Гидроксизин".
- Hydroxyzine sameAs Hydroxyzin.
- Hydroxyzine sameAs Hidroxicina.
- Hydroxyzine sameAs Hydroxyzine.
- Hydroxyzine sameAs Idroxizina.
- Hydroxyzine sameAs Hydroksyzyna.
- Hydroxyzine sameAs Hidroxizina.
- Hydroxyzine sameAs m.036pyy.
- Hydroxyzine sameAs Q421937.
- Hydroxyzine sameAs Q421937.
- Hydroxyzine sameAs hydroxyzine.
- Hydroxyzine sameAs DB00557.
- Hydroxyzine sameAs 3658.
- Hydroxyzine wasDerivedFrom Hydroxyzine?oldid=606741525.
- Hydroxyzine depiction Hydroxyzine.svg.
- Hydroxyzine isPrimaryTopicOf Hydroxyzine.