Matches in DBpedia 2014 for { <http://dbpedia.org/resource/IDH2> ?p ?o. }
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- IDH2 abstract "Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene.Isocitrate dehydrogenases are enzymes that catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by the IDH2 gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Somatic mosaic mutations of this gene have also been found associated to Ollier disease and Maffucci syndrome.".
- IDH2 entrezgene "3418".
- IDH2 wikiPageID "14877730".
- IDH2 wikiPageRevisionID "589390044".
- IDH2 hasPhotoCollection IDH2.
- IDH2 requireManualInspection "no".
- IDH2 updateCitations "yes".
- IDH2 updatePage "yes".
- IDH2 updateProteinBox "yes".
- IDH2 updateSummary "yes".
- IDH2 type Biomolecule.
- IDH2 type Protein.
- IDH2 type BiologicalObject.
- IDH2 comment "Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene.Isocitrate dehydrogenases are enzymes that catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).".
- IDH2 label "IDH2".
- IDH2 sameAs IDH2.
- IDH2 sameAs m.03g__5d.
- IDH2 sameAs Q5970028.
- IDH2 sameAs Q5970028.
- IDH2 sameAs 2313.
- IDH2 wasDerivedFrom IDH2?oldid=589390044.
- IDH2 isPrimaryTopicOf IDH2.