Matches in DBpedia 2014 for { <http://dbpedia.org/resource/INCENP> ?p ?o. }
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- INCENP abstract "Inner centromere protein is a protein that in humans is encoded by the INCENP gene.In mammalian cells, two broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger' (or transiently interacting) proteins. The constitutive proteins include CENPA (centromere protein A), CENPB, CENPC1, and CENPD.The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE; MCAK; KID; cytoplasmic dynein (e.g., DYNC1H1); CliPs (e.g. CLIP1); and CENPF/mitosin (CENPF). The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis.INCENP is a regulatory protein in the chromosome passenger complex. It is involved in regulation of the catalytic protein Aurora B. It performs this function in association with two other proteins - Survivin and Borealin. These proteins form a tight three-helical bundle. The N-terminal domain of INCENP is the domain involved in formation of this three-helical bundle.".
- INCENP entrezgene "3619".
- INCENP symbol "INCENP_ARK-bind".
- INCENP symbol "INCENP_N".
- INCENP wikiPageID "14766680".
- INCENP wikiPageRevisionID "591783999".
- INCENP caption "crystal structure of a survivin-borealin-incenp core complex".
- INCENP caption "crystal structure of aurora b kinase in complex with a aminothiazole inhibitor".
- INCENP hasPhotoCollection INCENP.
- INCENP interpro "IPR005635".
- INCENP interpro "IPR022006".
- INCENP name "Chromosome passenger complex protein INCENP N terminal".
- INCENP name "Inner centromere protein, ARK binding region".
- INCENP pfam "PF03941".
- INCENP pfam "PF12178".
- INCENP requireManualInspection "no".
- INCENP symbol "INCENP_ARK-bind".
- INCENP symbol "INCENP_N".
- INCENP updateCitations "yes".
- INCENP updatePage "yes".
- INCENP updateProteinBox "yes".
- INCENP updateSummary "no".
- INCENP subject Category:Protein_families.
- INCENP type Abstraction100002137.
- INCENP type Family108078020.
- INCENP type Group100031264.
- INCENP type Organization108008335.
- INCENP type ProteinFamilies.
- INCENP type SocialGroup107950920.
- INCENP type Unit108189659.
- INCENP type YagoLegalActor.
- INCENP type YagoLegalActorGeo.
- INCENP type YagoPermanentlyLocatedEntity.
- INCENP type Biomolecule.
- INCENP type Protein.
- INCENP type BiologicalObject.
- INCENP comment "Inner centromere protein is a protein that in humans is encoded by the INCENP gene.In mammalian cells, two broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger' (or transiently interacting) proteins.".
- INCENP label "INCENP".
- INCENP sameAs m.03gx8sd.
- INCENP sameAs Q15996692.
- INCENP sameAs Q15996692.
- INCENP sameAs INCENP.
- INCENP wasDerivedFrom INCENP?oldid=591783999.
- INCENP isPrimaryTopicOf INCENP.