Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ING3> ?p ?o. }
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- ING3 abstract "Inhibitor of growth protein 3 is a protein that in humans is encoded by the ING3 gene.The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.".
- ING3 entrezgene "54556".
- ING3 wikiPageID "15063480".
- ING3 wikiPageRevisionID "591794920".
- ING3 hasPhotoCollection ING3.
- ING3 requireManualInspection "no".
- ING3 summaryText "The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.".
- ING3 updateCitations "yes".
- ING3 updatePage "yes".
- ING3 updateProteinBox "yes".
- ING3 updateSummary "yes".
- ING3 type Biomolecule.
- ING3 type Protein.
- ING3 type BiologicalObject.
- ING3 comment "Inhibitor of growth protein 3 is a protein that in humans is encoded by the ING3 gene.The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax.".
- ING3 label "ING3".
- ING3 sameAs m.03hg7q2.
- ING3 sameAs Q5972282.
- ING3 sameAs Q5972282.
- ING3 wasDerivedFrom ING3?oldid=591794920.
- ING3 isPrimaryTopicOf ING3.