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- ITGA7 abstract "Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene.ITGA7 encodes integrin alpha chain 7. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 7 undergoes post-translational cleavage within the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. Alpha 7 beta 1 is the major integrin complex expressed in differentiated muscle cells. Splice variants of alpha 7 that differ in both the extracellular and cytoplasmic domains exist in the mouse; however, to date only a single human transcript type has been isolated: it contains extracellular and cytoplasmic domains corresponding to the mouse X2 and B variants, respectively. A unique extracellular splice variant has been identified in human, although it clearly represents a minor species and its biological significance is unclear.".
- ITGA7 entrezgene "3679".
- ITGA7 wikiPageExternalLink report.cgi?report=orth_overview&gene_id=3679.
- ITGA7 wikiPageExternalLink index.shtml.
- ITGA7 wikiPageID "14757777".
- ITGA7 wikiPageRevisionID "591869046".
- ITGA7 hasPhotoCollection ITGA7.
- ITGA7 requireManualInspection "no".
- ITGA7 summaryText "ITGA7 encodes integrin alpha chain 7. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 7 undergoes post-translational cleavage within the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. Alpha 7 beta 1 is the major integrin complex expressed in differentiated muscle cells. Splice variants of alpha 7 that differ in both the extracellular and cytoplasmic domains exist in the mouse; however, to date only a single human transcript type has been isolated: it contains extracellular and cytoplasmic domains corresponding to the mouse X2 and B variants, respectively. A unique extracellular splice variant has been identified in human, although it clearly represents a minor species and its biological significance is unclear.".
- ITGA7 updateCitations "yes".
- ITGA7 updatePage "yes".
- ITGA7 updateProteinBox "yes".
- ITGA7 updateSummary "yes".
- ITGA7 type Biomolecule.
- ITGA7 type Protein.
- ITGA7 type BiologicalObject.
- ITGA7 comment "Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene.ITGA7 encodes integrin alpha chain 7. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 7 undergoes post-translational cleavage within the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1.".
- ITGA7 label "ITGA7".
- ITGA7 label "ITGA7".
- ITGA7 label "Интегрин альфа-7".
- ITGA7 sameAs ITGA7.
- ITGA7 sameAs m.03gwx_9.
- ITGA7 sameAs Q4201955.
- ITGA7 sameAs Q4201955.
- ITGA7 sameAs ITGA7.
- ITGA7 wasDerivedFrom ITGA7?oldid=591869046.
- ITGA7 isPrimaryTopicOf ITGA7.