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- Indalpine abstract "Indalpine (Upstène, LM-5008) is an selective serotonin reuptake inhibitor (SSRI) class drug that was discovered in 1977 by the pharmacologists Le Fur and Uzan at Pharmuka, a small French pharmaceutical firm, who credit Baron Shopsin and his colleagues at NYU-Bellevue/NYU School of Medicine in New York with providing the basis for their work. They were particularly influenced by the series of "synthesis inhibitor studies" carried out by Shopsin's team during the early to mid 70's, and in particular, the clinical report by Shopsin et al.(1976) relating to PCPA's rapid reversal of antidepressant response to tranylcypromine in depressed patients. This led to an understanding of the role of the monoamine neurotransmitter serotonin (5-hydroxytryptamine, or 5HT) in the therapeutic effects of the available tricyclic and MAOI class antidepressants. The studies led to widespread recognition of a serotonin hypothesis of depression, contradicting theories that promoted the role of norepinephrine.".
- Indalpine fdaUniiCode "V35562QSVT".
- Indalpine iupacName "3-(2-piperidin-4-ylethyl)-1H-indole".
- Indalpine thumbnail Indalpine.png?width=300.
- Indalpine wikiPageID "12864659".
- Indalpine wikiPageRevisionID "583973979".
- Indalpine date "April 2013".
- Indalpine hasPhotoCollection Indalpine.
- Indalpine imagefile "Indalpine.png".
- Indalpine imagesize "150".
- Indalpine iupacname "3".
- Indalpine reason "designated by who?".
- Indalpine unii "V35562QSVT".
- Indalpine verifiedfields "changed".
- Indalpine verifiedrevid "464369525".
- Indalpine subject Category:Antidepressants.
- Indalpine subject Category:Indoles.
- Indalpine subject Category:Piperidines.
- Indalpine subject Category:Selective_serotonin_reuptake_inhibitors.
- Indalpine type Inhibitor114724436.
- Indalpine type Matter100020827.
- Indalpine type MonoamineReuptakeInhibitors.
- Indalpine type PhysicalEntity100001930.
- Indalpine type Substance100020090.
- Indalpine type ChemicalCompound.
- Indalpine type ChemicalSubstance.
- Indalpine type ChemicalSubstanceType.
- Indalpine type ChemicalObject.
- Indalpine type Thing.
- Indalpine comment "Indalpine (Upstène, LM-5008) is an selective serotonin reuptake inhibitor (SSRI) class drug that was discovered in 1977 by the pharmacologists Le Fur and Uzan at Pharmuka, a small French pharmaceutical firm, who credit Baron Shopsin and his colleagues at NYU-Bellevue/NYU School of Medicine in New York with providing the basis for their work.".
- Indalpine label "Indalpine".
- Indalpine sameAs m.02x8hs2.
- Indalpine sameAs Q6015666.
- Indalpine sameAs Q6015666.
- Indalpine sameAs Indalpine.
- Indalpine wasDerivedFrom Indalpine?oldid=583973979.
- Indalpine depiction Indalpine.png.
- Indalpine isPrimaryTopicOf Indalpine.
