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- Induced_coma abstract "A barbiturate-induced coma, or barb coma, is a temporary coma (a deep state of unconsciousness) brought on by a controlled dose of a barbiturate drug, usually pentobarbital or thiopental. Barbiturate comas are used to protect the brain during major neurosurgery, and as a last line of treatment in certain cases of status epilepticus that have not responded to other treatments.Barbiturates reduce the metabolic rate of brain tissue, as well as the cerebral blood flow. With these reductions, the blood vessels in the brain narrow, decreasing the amount of space occupied by the brain, and hence the intracranial pressure. The hope is that, with the swelling relieved, the pressure decreases and some or all brain damage may be averted. Several studies have supported this theory by showing reduced mortality when treating refractory intracranial hypertension with a barbiturate coma.Controversy exists, however, over the benefits of using barbiturates to control intracranial hypertension. Some studies have shown that barbiturate-induced coma can reduce intracranial hypertension but does not necessarily prevent brain damage. Furthermore, the reduction in intracranial hypertension may not be sustained. Some randomized trials have failed to demonstrate any survival or morbidity benefit of induced coma in diverse conditions such as neurosurgical operations, head trauma, intracranial aneurysm rupture, intracranial hemorrhage, ischemic stroke, and status epilepticus. If the patient survives, cognitive impairment may also follow recovery from the coma.About 55% of the glucose and oxygen utilisation by the brain is meant for its electrical activity and the rest for all other activities such as metabolism.[citation needed] This is recognized by a device such as an electroencephalogram (EEG), which measures electrical activity in the brain. When barbiturates are given to brain injured patients for induced coma, they act by reducing the electrical activity of the brain, which in theory reduces the metabolic and oxygen demand.[citation needed] Once there is improvement in the patient's general condition, the barbiturates are withdrawn gradually and the patient regains consciousness.Induced coma was used in the treatment of symptomatic rabies through the Milwaukee protocol.".
- Induced_coma wikiPageID "1275750".
- Induced_coma wikiPageRevisionID "594007995".
- Induced_coma hasPhotoCollection Induced_coma.
- Induced_coma subject Category:Coma.
- Induced_coma subject Category:Intensive_care_medicine.
- Induced_coma subject Category:Neurology_procedures.
- Induced_coma type Abstraction100002137.
- Induced_coma type Act100030358.
- Induced_coma type Activity100407535.
- Induced_coma type Event100029378.
- Induced_coma type NeurologyProcedures.
- Induced_coma type Procedure101023820.
- Induced_coma type PsychologicalFeature100023100.
- Induced_coma type YagoPermanentlyLocatedEntity.
- Induced_coma comment "A barbiturate-induced coma, or barb coma, is a temporary coma (a deep state of unconsciousness) brought on by a controlled dose of a barbiturate drug, usually pentobarbital or thiopental. Barbiturate comas are used to protect the brain during major neurosurgery, and as a last line of treatment in certain cases of status epilepticus that have not responded to other treatments.Barbiturates reduce the metabolic rate of brain tissue, as well as the cerebral blood flow.".
- Induced_coma label "Coma farmacologico".
- Induced_coma label "Coma induzido".
- Induced_coma label "Induced coma".
- Induced_coma label "Искусственная кома".
- Induced_coma sameAs Coma_farmacologico.
- Induced_coma sameAs Coma_induzido.
- Induced_coma sameAs m.04pc6z.
- Induced_coma sameAs Q933408.
- Induced_coma sameAs Q933408.
- Induced_coma sameAs Induced_coma.
- Induced_coma wasDerivedFrom Induced_coma?oldid=594007995.
- Induced_coma isPrimaryTopicOf Induced_coma.