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- Inosine abstract "Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond.Inosine is commonly found in tRNAs and is essential for proper translation of the genetic code in wobble base pairs.Knowledge of inosine metabolism has led to advances in immunotherapy in recent decades. Inosine monophosphate is oxidised by the enzyme inosine monophosphate dehydrogenase, yielding xanthosine monophosphate, a key precursor in purine metabolism. Mycophenolate mofetil is an anti-metabolite, anti-proliferative drug that acts as an inhibitor of inosine monophosphate dehydrogenase. It is used in the treatment of a variety of autoimmune diseases including Wegener's granulomatosis because the uptake of purine by actively dividing B cells can exceed 8 times that of normal body cells, and, therefore, this set of white cells (which cannot operate purine salvage pathways) is selectively targeted by the purine deficiency resulting from IMD inhibition.".
- Inosine atcPrefix "D06".
- Inosine atcSuffix "BB05".
- Inosine casNumber "58-63-9".
- Inosine chEBI "17596".
- Inosine drugbank "DB04566".
- Inosine fdaUniiCode "5A614L51CT".
- Inosine iupacName "9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one".
- Inosine pubchem "6021".
- Inosine thumbnail Inosin.svg?width=300.
- Inosine wikiPageExternalLink news111.htm.
- Inosine wikiPageExternalLink neuhausing.htm.
- Inosine wikiPageExternalLink ino_0144.shtml.
- Inosine wikiPageID "89111".
- Inosine wikiPageRevisionID "599840308".
- Inosine atcPrefix "D06".
- Inosine atcSuffix "BB05".
- Inosine c "10".
- Inosine casNumber "58".
- Inosine chebi "17596".
- Inosine chembl "1556".
- Inosine chemspiderid "5799".
- Inosine drugbank "DB04566".
- Inosine h "12".
- Inosine hasPhotoCollection Inosine.
- Inosine image "Inosine ball-and-stick.png".
- Inosine inchi "1".
- Inosine iupacName "9".
- Inosine kegg "294.0".
- Inosine legalStatus "OTC".
- Inosine metabolism Liver.
- Inosine molecularWeight "268.23".
- Inosine n "4".
- Inosine o "5".
- Inosine pubchem "6021".
- Inosine smiles "c1[nH]c2cncn2[C@H]3[C@@H]O".
- Inosine stdinchi "1".
- Inosine stdinchikey "UGQMRVRMYYASKQ-KQYNXXCUSA-N".
- Inosine unii "5".
- Inosine verifiedfields "changed".
- Inosine verifiedrevid "461935819".
- Inosine watchedfields "changed".
- Inosine subject Category:Antivirals.
- Inosine subject Category:Nucleosides.
- Inosine subject Category:Purines.
- Inosine type Drug.
- Inosine type DrugProduct.
- Inosine type FunctionalSubstance.
- Inosine comment "Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond.Inosine is commonly found in tRNAs and is essential for proper translation of the genetic code in wobble base pairs.Knowledge of inosine metabolism has led to advances in immunotherapy in recent decades.".
- Inosine label "Inosin".
- Inosine label "Inosina".
- Inosine label "Inosina".
- Inosine label "Inosina".
- Inosine label "Inosine".
- Inosine label "Inosine".
- Inosine label "Inozyna".
- Inosine label "Инозин".
- Inosine label "イノシン".
- Inosine label "肌苷".
- Inosine sameAs Inosin.
- Inosine sameAs Inosin.
- Inosine sameAs Inosina.
- Inosine sameAs Inosine.
- Inosine sameAs Inosina.
- Inosine sameAs イノシン.
- Inosine sameAs Inozyna.
- Inosine sameAs Inosina.
- Inosine sameAs m.0m886.
- Inosine sameAs Q422564.
- Inosine sameAs Q422564.
- Inosine wasDerivedFrom Inosine?oldid=599840308.
- Inosine depiction Inosin.svg.
- Inosine isPrimaryTopicOf Inosine.