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- Integrin abstract "Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). In signal transduction, integrins pass information about the chemical composition and mechanical status of the ECM into the cell. Therefore, in addition to transmitting mechanical forces across otherwise vulnerable membranes, they are involved in cell signaling and the regulation of cell cycle, shape, and motility.Typically, receptors inform a cell of the molecules in its environment and the cell responds. Not only do integrins perform this outside-in signaling, but they also operate an inside-out mode. Thus, they transduce information from the ECM to the cell, as well as reveal the status of the cell to the outside, allowing rapid and flexible responses to changes in the environment, for example to allow blood coagulation by platelets.There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all animals and have been found in all animals investigated, from sponges to mammals[citation needed]. Integrins have been extensively studied in humans.Integrins work alongside other proteins such as cadherins, immunoglobulin superfamily cell adhesion molecules, selectins and syndecans to mediate cell–cell and cell–matrix interaction and communication. Integrins bind cell surface and ECM components such as fibronectin, vitronectin, collagen, and laminin.".
- Integrin symbol "Integrin_alpha".
- Integrin symbol "Integrin_alphaVbeta3".
- Integrin symbol "Integrin_b_cyt".
- Integrin symbol "Integrin_beta".
- Integrin thumbnail PDB_1jv2_EBI.jpg?width=300.
- Integrin wikiPageExternalLink integrin.php.
- Integrin wikiPageExternalLink go-0007229.
- Integrin wikiPageExternalLink go-0033622.
- Integrin wikiPageExternalLink watch?v=8DOTnKHFTTg.
- Integrin wikiPageID "15302".
- Integrin wikiPageRevisionID "606211542".
- Integrin caption "Structure of chaperone protein PAPD.".
- Integrin caption "Structure of the extracellular segment of integrin alpha Vbeta3.".
- Integrin caption "crystal structure of the filamin a repeat 21 complexed with the integrin beta7 cytoplasmic tail peptide".
- Integrin hasPhotoCollection Integrin.
- Integrin interpro "IPR000413".
- Integrin interpro "IPR002369".
- Integrin interpro "IPR013649".
- Integrin interpro "IPR014836".
- Integrin name "Integrin alpha cytoplasmic region".
- Integrin name "Integrin alphavbeta3 extracellular domains".
- Integrin name "Integrin beta 7 cytoplasmic domain: complex with filamin".
- Integrin name "Integrin, beta chain".
- Integrin opmFamily "197".
- Integrin opmProtein "2".
- Integrin pdb ", , , , , , , , , , , , , ,".
- Integrin pdb ", , , , ,".
- Integrin pdb ", , ,".
- Integrin pfam "PF00357".
- Integrin pfam "PF00362".
- Integrin pfam "PF08441".
- Integrin pfam "PF08725".
- Integrin pfamClan "CL0159".
- Integrin prosite "PDOC00215".
- Integrin prosite "PDOC00216".
- Integrin scop "1".
- Integrin smart "SM00187".
- Integrin symbol "Integrin_alpha".
- Integrin symbol "Integrin_alphaVbeta3".
- Integrin symbol "Integrin_b_cyt".
- Integrin symbol "Integrin_beta".
- Integrin subject Category:Cell_adhesion_proteins.
- Integrin subject Category:Integrins.
- Integrin subject Category:Transmembrane_proteins.
- Integrin type Abstraction100002137.
- Integrin type CellAdhesionProteins.
- Integrin type Chemical114806838.
- Integrin type Compound114818238.
- Integrin type Macromolecule114944888.
- Integrin type Material114580897.
- Integrin type Matter100020827.
- Integrin type Molecule114682133.
- Integrin type OrganicCompound114727670.
- Integrin type Part113809207.
- Integrin type PhysicalEntity100001930.
- Integrin type Protein114728724.
- Integrin type Relation100031921.
- Integrin type Substance100019613.
- Integrin type Thing100002452.
- Integrin type TransmembraneProteins.
- Integrin type Unit109465459.
- Integrin type Biomolecule.
- Integrin type Protein.
- Integrin type BiologicalObject.
- Integrin comment "Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). In signal transduction, integrins pass information about the chemical composition and mechanical status of the ECM into the cell.".
- Integrin label "Integrin".
- Integrin label "Integrin".
- Integrin label "Integrina".
- Integrin label "Integrina".
- Integrin label "Integrina".
- Integrin label "Integryny".
- Integrin label "Intégrine".
- Integrin label "Интегрин".
- Integrin label "إنتغرين".
- Integrin label "インテグリン".
- Integrin label "整合素".
- Integrin sameAs Integrin.
- Integrin sameAs Integrin.
- Integrin sameAs Integrina.
- Integrin sameAs Intégrine.
- Integrin sameAs Integrina.
- Integrin sameAs インテグリン.
- Integrin sameAs Integryny.
- Integrin sameAs Integrina.
- Integrin sameAs m.03yk6.
- Integrin sameAs Q409715.
- Integrin sameAs Q409715.
- Integrin sameAs Integrin.
- Integrin wasDerivedFrom Integrin?oldid=606211542.
- Integrin depiction PDB_1jv2_EBI.jpg.
- Integrin isPrimaryTopicOf Integrin.
