Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Integrin-linked_kinase> ?p ?o. }
Showing items 1 to 39 of
39
with 100 items per page.
- Integrin-linked_kinase abstract "Integrin-linked kinase (ILK) is a 59kDa protein originally identified while conducting a yeast-two hybrid screen with integrin β1 as the bait protein (Hannigan et al., 1996). Since its discovery, ILK has been associated with multiple cellular functions including cell migration, cell proliferation, cell-adhesions, and signal transduction.Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.In 2008, ILK was found to localize to the centrosome and regulate mitotic spindle organization.".
- Integrin-linked_kinase entrezgene "3611".
- Integrin-linked_kinase wikiPageID "9631618".
- Integrin-linked_kinase wikiPageRevisionID "591801210".
- Integrin-linked_kinase hasPhotoCollection Integrin-linked_kinase.
- Integrin-linked_kinase requireManualInspection "no".
- Integrin-linked_kinase summaryText "Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase , interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.".
- Integrin-linked_kinase updateCitations "yes".
- Integrin-linked_kinase updatePage "yes".
- Integrin-linked_kinase updateProteinBox "yes".
- Integrin-linked_kinase updateSummary "no".
- Integrin-linked_kinase subject Category:Proteins.
- Integrin-linked_kinase type Abstraction100002137.
- Integrin-linked_kinase type Chemical114806838.
- Integrin-linked_kinase type Compound114818238.
- Integrin-linked_kinase type Macromolecule114944888.
- Integrin-linked_kinase type Material114580897.
- Integrin-linked_kinase type Matter100020827.
- Integrin-linked_kinase type Molecule114682133.
- Integrin-linked_kinase type OrganicCompound114727670.
- Integrin-linked_kinase type Part113809207.
- Integrin-linked_kinase type PhysicalEntity100001930.
- Integrin-linked_kinase type Protein114728724.
- Integrin-linked_kinase type Proteins.
- Integrin-linked_kinase type Relation100031921.
- Integrin-linked_kinase type Substance100019613.
- Integrin-linked_kinase type Thing100002452.
- Integrin-linked_kinase type Unit109465459.
- Integrin-linked_kinase type Biomolecule.
- Integrin-linked_kinase type Protein.
- Integrin-linked_kinase type BiologicalObject.
- Integrin-linked_kinase comment "Integrin-linked kinase (ILK) is a 59kDa protein originally identified while conducting a yeast-two hybrid screen with integrin β1 as the bait protein (Hannigan et al., 1996).".
- Integrin-linked_kinase label "Integrin-linked kinase".
- Integrin-linked_kinase sameAs m.02pmhx5.
- Integrin-linked_kinase sameAs Q11913806.
- Integrin-linked_kinase sameAs Q11913806.
- Integrin-linked_kinase sameAs Integrin-linked_kinase.
- Integrin-linked_kinase wasDerivedFrom Integrin-linked_kinase?oldid=591801210.
- Integrin-linked_kinase isPrimaryTopicOf Integrin-linked_kinase.