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- Interleukin_12_receptor,_beta_1_subunit abstract "Interleukin 12 receptor, beta 1 is a subunit of the interleukin 12 receptor. IL12RB1, is its human gene. IL12RB1 is also known as CD212 (cluster of differentiation 212).The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.".
- Interleukin_12_receptor,_beta_1_subunit entrezgene "3594".
- Interleukin_12_receptor,_beta_1_subunit wikiPageID "14757761".
- Interleukin_12_receptor,_beta_1_subunit wikiPageRevisionID "584816691".
- Interleukin_12_receptor,_beta_1_subunit hasPhotoCollection Interleukin_12_receptor,_beta_1_subunit.
- Interleukin_12_receptor,_beta_1_subunit requireManualInspection "no".
- Interleukin_12_receptor,_beta_1_subunit summaryText "The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.".
- Interleukin_12_receptor,_beta_1_subunit updateCitations "yes".
- Interleukin_12_receptor,_beta_1_subunit updatePage "yes".
- Interleukin_12_receptor,_beta_1_subunit updateProteinBox "yes".
- Interleukin_12_receptor,_beta_1_subunit updateSummary "yes".
- Interleukin_12_receptor,_beta_1_subunit subject Category:Clusters_of_differentiation.
- Interleukin_12_receptor,_beta_1_subunit type Biomolecule.
- Interleukin_12_receptor,_beta_1_subunit type Protein.
- Interleukin_12_receptor,_beta_1_subunit type BiologicalObject.
- Interleukin_12_receptor,_beta_1_subunit comment "Interleukin 12 receptor, beta 1 is a subunit of the interleukin 12 receptor. IL12RB1, is its human gene. IL12RB1 is also known as CD212 (cluster of differentiation 212).The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex.".
- Interleukin_12_receptor,_beta_1_subunit label "Interleukin 12 receptor, beta 1 subunit".
- Interleukin_12_receptor,_beta_1_subunit sameAs m.03gwxzm.
- Interleukin_12_receptor,_beta_1_subunit sameAs Q6046976.
- Interleukin_12_receptor,_beta_1_subunit sameAs Q6046976.
- Interleukin_12_receptor,_beta_1_subunit sameAs IL12RB1.
- Interleukin_12_receptor,_beta_1_subunit wasDerivedFrom Interleukin_12_receptor,_beta_1_subunit?oldid=584816691.
- Interleukin_12_receptor,_beta_1_subunit isPrimaryTopicOf Interleukin_12_receptor,_beta_1_subunit.