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Interleukin_17 abstract "Interleukin 17A (IL-17 or IL-17A), originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993, is the founding member of a group of cytokines called the IL-17 family. Known as CTLA8 in rodents, IL-17 shows high homology to viral IL-17 encoded by an open reading frame of the T-lymphotropic rhadinovirus Herpesvirus saimiri.Interleukin 17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to Interferon gamma. IL-17 is produced by T-helper cells and is induced by IL–23 which results in destructive tissue damage in delayed-type reactions. Interleukin 17 as a family functions as a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen’s cellular matrix. Interleukin 17 acts synergistically with tumor necrosis factor and interleukin-1.To elicit its functions, IL-17 binds to a type I cell surface receptor called IL-17R of which there are at least three variants IL17RA, IL17RB, and IL17RC.".
Interleukin_17 arm "p".
Interleukin_17 arm "q".
Interleukin_17 band "11".
Interleukin_17 band "11.2".
Interleukin_17 band "12".
Interleukin_17 band "24".
Interleukin_17 band "32-34".
Interleukin_17 chromosome "13".
Interleukin_17 chromosome "14".
Interleukin_17 chromosome "16".
Interleukin_17 chromosome "5".
Interleukin_17 chromosome "6".
Interleukin_17 entrezgene "112744".
Interleukin_17 entrezgene "27190".
Interleukin_17 entrezgene "271989".
Interleukin_17 entrezgene "3605".
Interleukin_17 entrezgene "53342".
Interleukin_17 entrezgene "64806".
Interleukin_17 hgncid "13765".
Interleukin_17 hgncid "16404".
Interleukin_17 hgncid "5981".
Interleukin_17 hgncid "5982".
Interleukin_17 hgncid "5983".
Interleukin_17 hgncid "5984".
Interleukin_17 omim "603149".
Interleukin_17 omim "604627".
Interleukin_17 omim "604628".
Interleukin_17 omim "605658".
Interleukin_17 omim "606496".
Interleukin_17 omim "607587".
Interleukin_17 pdb "1JPY".
Interleukin_17 refseq "NP_002181".
Interleukin_17 refseq "NP_037410".
Interleukin_17 refseq "NP_055258".
Interleukin_17 refseq "NP_073626".
Interleukin_17 refseq "NP_443104".
Interleukin_17 refseq "NP_612141".
Interleukin_17 symbol ", CX2".
Interleukin_17 symbol "IL-25".
Interleukin_17 symbol "IL17, CTLA8".
Interleukin_17 symbol "IL17A".
Interleukin_17 symbol "IL17B".
Interleukin_17 symbol "IL17C".
Interleukin_17 symbol "IL17D".
Interleukin_17 symbol "IL17E".
Interleukin_17 symbol "IL17F".
Interleukin_17 symbol "ML-1".
Interleukin_17 symbol "ZCOTO7".
Interleukin_17 thumbnail IL17F_1JPY.png?width=300.
Interleukin_17 uniprot "Q16552".
Interleukin_17 uniprot "Q8TAD2".
Interleukin_17 uniprot "Q96PD4".
Interleukin_17 uniprot "Q9H293".
Interleukin_17 uniprot "Q9P0M4".
Interleukin_17 uniprot "Q9UHF5".
Interleukin_17 wikiPageID "7867155".
Interleukin_17 wikiPageRevisionID "591804103".
Interleukin_17 altsymbols Interleukin_25.
Interleukin_17 altsymbols ", CX2".
Interleukin_17 altsymbols "IL17, CTLA8".
Interleukin_17 altsymbols "ML-1".
Interleukin_17 altsymbols "ZCOTO7".
Interleukin_17 arm "p".
Interleukin_17 arm "q".
Interleukin_17 band "11".
Interleukin_17 band "11.2".
Interleukin_17 band "12".
Interleukin_17 band "24".
Interleukin_17 band "32".
Interleukin_17 caption "Crystallographic structure of dimeric human IL-17f.".
Interleukin_17 chromosome "13".
Interleukin_17 chromosome "14".
Interleukin_17 chromosome "16".
Interleukin_17 chromosome "5".
Interleukin_17 chromosome "6".
Interleukin_17 entrezgene "112744".
Interleukin_17 entrezgene "27190".
Interleukin_17 entrezgene "271989".
Interleukin_17 entrezgene "3605".
Interleukin_17 entrezgene "53342".
Interleukin_17 entrezgene "64806".
Interleukin_17 hasPhotoCollection Interleukin_17.
Interleukin_17 hgncid "13765".
Interleukin_17 hgncid "16404".
Interleukin_17 hgncid "5981".
Interleukin_17 hgncid "5982".
Interleukin_17 hgncid "5983".
Interleukin_17 hgncid "5984".
Interleukin_17 name IL17A.
Interleukin_17 name "Interleukin 17B".
Interleukin_17 name "Interleukin 17C".
Interleukin_17 name "Interleukin 17D".
Interleukin_17 name "Interleukin 17E".
Interleukin_17 name "Interleukin 17F".
Interleukin_17 omim "603149".
Interleukin_17 omim "604627".
Interleukin_17 omim "604628".
Interleukin_17 omim "605658".
Interleukin_17 omim "606496".