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- International_Mouse_Phenotyping_Consortium abstract "The International Mouse Phenotyping Consortium (IMPC) is an international scientific endeavour to create and characterize the phenotype of 20,000 knockout mouse strains. Launched in September 2011, the consortium consists of over 15 research institutes across four continents with funding provided by the NIH, European national governments and the partner institutions.The initiative is projected to take 10 years (until 2021), and will focus on analysing homozygous mutant mice generated on an isogenic C57BL/6N background by the International Knockout Mouse Consortium. The mouse strains are characterized in a broad based phenotyping pipeline that is focused on revealing insights into human disease by measuring embryonic, neuromuscular, sensory, cardiovascular, metabolic, respiratory, haematological, and neurological parameters.The protocols used to assess these phenotypes have been standardized across the IMPC partners and are available at IMPReSS.Mouse strains generated by the IMPC partners are deposited at the KOMP repository and the European Mutant Mouse Archive. In many cases, strains carrying one of two types of alleles will be archived - a null allele used in the primary IMPC phenotyping pipeline and a conditional ready allele that allows tissue restricted knockouts via the Cre-Lox Recombination and FLP-FRT recombination systems.The phenotypic data is recorded in a freely accessible, fully searchable online database, generating what has been described as a "comprehensive encyclopaedia of mammalian gene function."".
- International_Mouse_Phenotyping_Consortium title "IMPReSS".
- International_Mouse_Phenotyping_Consortium title "International Mouse Phenotyping Consortium".
- International_Mouse_Phenotyping_Consortium wikiPageExternalLink www.mousephenotype.org.
- International_Mouse_Phenotyping_Consortium wikiPageExternalLink impress.
- International_Mouse_Phenotyping_Consortium wikiPageID "38950795".
- International_Mouse_Phenotyping_Consortium wikiPageRevisionID "591807335".
- International_Mouse_Phenotyping_Consortium description "Encyclopaedia of phenotypes from knockout mice.".
- International_Mouse_Phenotyping_Consortium description "Standardized protocols for phenotyping mutant mouse strains.".
- International_Mouse_Phenotyping_Consortium hasPhotoCollection International_Mouse_Phenotyping_Consortium.
- International_Mouse_Phenotyping_Consortium logo "200".
- International_Mouse_Phenotyping_Consortium organism House_mouse.
- International_Mouse_Phenotyping_Consortium organism Mouse.
- International_Mouse_Phenotyping_Consortium pmid "Brown and Moore, 2012".
- International_Mouse_Phenotyping_Consortium released "2011".
- International_Mouse_Phenotyping_Consortium released "2012".
- International_Mouse_Phenotyping_Consortium title "IMPReSS".
- International_Mouse_Phenotyping_Consortium title "International Mouse Phenotyping Consortium".
- International_Mouse_Phenotyping_Consortium url www.mousephenotype.org.
- International_Mouse_Phenotyping_Consortium url impress.
- International_Mouse_Phenotyping_Consortium description "Encyclopaedia of phenotypes from knockout mice.".
- International_Mouse_Phenotyping_Consortium description "Standardized protocols for phenotyping mutant mouse strains.".
- International_Mouse_Phenotyping_Consortium subject Category:Biological_databases.
- International_Mouse_Phenotyping_Consortium subject Category:Genetically_modified_organisms.
- International_Mouse_Phenotyping_Consortium subject Category:Laboratory_mouse_breeds.
- International_Mouse_Phenotyping_Consortium type BiologicalDatabase.
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- International_Mouse_Phenotyping_Consortium comment "The International Mouse Phenotyping Consortium (IMPC) is an international scientific endeavour to create and characterize the phenotype of 20,000 knockout mouse strains.".
- International_Mouse_Phenotyping_Consortium label "International Mouse Phenotyping Consortium".
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- International_Mouse_Phenotyping_Consortium homepage www.mousephenotype.org.
- International_Mouse_Phenotyping_Consortium homepage impress.
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