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- Iodolactonization abstract "Iodolactonization (or, more generally, Halolactonization) is an organic reaction that forms a ring (the lactone) by the addition of an oxygen and iodine across a carbon-carbon double bond. The reaction was first reported by M. J. Bougalt in 1904 and has since become one of the most effective ways to synthesize lactones. Strengths of the reaction include the mild conditions and incorporation of the versatile iodine atom into the product.Iodolactonization has been used in the synthesis of many natural products including those with medicinal applications such as vernoplepin and vernomenin, two compounds used in tumor growth inhibition, and vibralactone, a pancreatic lipase inhibitor that has been used in the treatment of obesity. Iodolactonization has also been used by E.J. Corey to synthesize numerous prostaglandins. For his work in prostaglandin synthesis and other contributions to the field of organic chemistry, Corey was awarded the Nobel Prize in Chemistry in 1990.".
- Iodolactonization thumbnail IodolactonizationIntroduction.svg?width=300.
- Iodolactonization wikiPageID "12694871".
- Iodolactonization wikiPageRevisionID "544189609".
- Iodolactonization hasPhotoCollection Iodolactonization.
- Iodolactonization subject Category:Lactones.
- Iodolactonization subject Category:Organic_reactions.
- Iodolactonization type ChemicalProcess113446390.
- Iodolactonization type ChemicalReaction113447361.
- Iodolactonization type NaturalProcess113518963.
- Iodolactonization type OrganicReactions.
- Iodolactonization type PhysicalEntity100001930.
- Iodolactonization type Process100029677.
- Iodolactonization comment "Iodolactonization (or, more generally, Halolactonization) is an organic reaction that forms a ring (the lactone) by the addition of an oxygen and iodine across a carbon-carbon double bond. The reaction was first reported by M. J. Bougalt in 1904 and has since become one of the most effective ways to synthesize lactones.".
- Iodolactonization label "Iodolactonization".
- Iodolactonization sameAs m.0hrgz6v.
- Iodolactonization sameAs Q6062283.
- Iodolactonization sameAs Q6062283.
- Iodolactonization sameAs Iodolactonization.
- Iodolactonization wasDerivedFrom Iodolactonization?oldid=544189609.
- Iodolactonization depiction IodolactonizationIntroduction.svg.
- Iodolactonization isPrimaryTopicOf Iodolactonization.
