Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Isotretinoin> ?p ?o. }
Showing items 1 to 94 of
94
with 100 items per page.
- Isotretinoin abstract "Isotretinoin, INN, /ˌaɪsoʊtrɨˈtɪnoʊ.ɨn/, (also known as 13-cis retinoic acid) first marketed as Accutane by Hoffmann-La Roche, is a medication primarily used to treat cystic acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and can be used in the treatment of brain, pancreatic and other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body.Isotretinoin is primarily used as a treatment for severe acne. The most common adverse effects are a transient worsening of acne (lasting 2–3 weeks), dry lips (cheilitis), dry and fragile skin, and an increased susceptibility to sunburn. Uncommon and rare side effects include: muscle aches and pains (myalgias), headaches. Isotretinoin is known to cause birth defects due to in utero exposure because of the molecule's close resemblance to retinoic acid, a natural vitamin A derivative which controls normal embryonic development.In the United States a special procedure is required to obtain the pharmaceutical. In most other countries a consent form is required which explains these risks. Women taking isotretinoin must not get pregnant during, and for 1 month after isotretinoin therapy. Sexual abstinence, or effective contraception is mandatory during this period. Barrier methods by themselves (such as condoms) are not considered adequate due to the unacceptable failure rates of approximately 3%. Women who fall pregnant whilst on isotretinoin therapy are generally counselled to have a termination. Isotretinoin has no effect on male reproduction.There is little evidence in the medical literature linking isotretinoin use with depression and suicide. Despite this, there exists a popular misconception amongst the public that isotretinoin use commonly causes depression.In 2009, Roche decided to remove Accutane from the US market after juries had awarded millions of dollars in damages to former Accutane users over inflammatory bowel disease claims. Other common brands are Roaccutane (Hoffman-La Roche, known as Accutane in the United States before July 2009), Amnesteem (Mylan), Claravis (Barr), Absorica (Ranbaxy), and Isotroin (Cipla).".
- Isotretinoin atcPrefix "D10".
- Isotretinoin atcSuffix "AD04".
- Isotretinoin casNumber "4759-48-2".
- Isotretinoin chEBI "6067".
- Isotretinoin drugbank "DB00982".
- Isotretinoin fdaUniiCode "EH28UP18IF".
- Isotretinoin iupacName "(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid".
- Isotretinoin pubchem "5282379".
- Isotretinoin thumbnail Isotretinoin2DACS2.svg?width=300.
- Isotretinoin wikiPageExternalLink danby.html.
- Isotretinoin wikiPageExternalLink isotretinoin.html.
- Isotretinoin wikiPageID "229985".
- Isotretinoin wikiPageRevisionID "606782714".
- Isotretinoin atcPrefix "D10".
- Isotretinoin atcSuffix "AD04".
- Isotretinoin bioavailability "Variable".
- Isotretinoin c "20".
- Isotretinoin casNumber "4759".
- Isotretinoin chebi "6067".
- Isotretinoin chembl "547".
- Isotretinoin chemspiderid "4445539".
- Isotretinoin drugbank "DB00982".
- Isotretinoin eliminationHalfLife "72000.0".
- Isotretinoin excretion "Renal and fecal".
- Isotretinoin h "28".
- Isotretinoin hasPhotoCollection Isotretinoin.
- Isotretinoin image "Isotretinoin3Dan.gif".
- Isotretinoin inchi "1".
- Isotretinoin iupacName "-37".
- Isotretinoin kegg "D00348".
- Isotretinoin legalAu "S4".
- Isotretinoin legalUk "POM".
- Isotretinoin legalUs "Rx-only".
- Isotretinoin licenceUs "Isotretinoin".
- Isotretinoin medlineplus "a681043".
- Isotretinoin metabolism Liver.
- Isotretinoin molecularWeight "300.44".
- Isotretinoin o "2".
- Isotretinoin pregnancyAu "X".
- Isotretinoin pregnancyUs "X".
- Isotretinoin proteinBound "99.9".
- Isotretinoin pubchem "5282379".
- Isotretinoin routesOfAdministration "Oral, topical".
- Isotretinoin smiles "O=C\C=CC".
- Isotretinoin stdinchi "1".
- Isotretinoin stdinchikey "SHGAZHPCJJPHSC-XFYACQKRSA-N".
- Isotretinoin tradename "Accutane".
- Isotretinoin unii "EH28UP18IF".
- Isotretinoin verifiedrevid "477168707".
- Isotretinoin watchedfields "changed".
- Isotretinoin width "200".
- Isotretinoin width "250".
- Isotretinoin subject Category:Anti-acne_preparations.
- Isotretinoin subject Category:Retinoids.
- Isotretinoin type Abstraction100002137.
- Isotretinoin type Act100030358.
- Isotretinoin type Activity100407535.
- Isotretinoin type Anti-acnePreparations.
- Isotretinoin type Event100029378.
- Isotretinoin type Preparation101143040.
- Isotretinoin type PsychologicalFeature100023100.
- Isotretinoin type YagoPermanentlyLocatedEntity.
- Isotretinoin type Drug.
- Isotretinoin type DrugProduct.
- Isotretinoin type FunctionalSubstance.
- Isotretinoin comment "Isotretinoin, INN, /ˌaɪsoʊtrɨˈtɪnoʊ.ɨn/, (also known as 13-cis retinoic acid) first marketed as Accutane by Hoffmann-La Roche, is a medication primarily used to treat cystic acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and can be used in the treatment of brain, pancreatic and other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis.".
- Isotretinoin label "Isotretinoin".
- Isotretinoin label "Isotretinoin".
- Isotretinoin label "Isotretinoina".
- Isotretinoin label "Isotretinoína".
- Isotretinoin label "Isotretinoína".
- Isotretinoin label "Isotretinoïne".
- Isotretinoin label "Isotrétinoïne".
- Isotretinoin label "Izotretynoina".
- Isotretinoin label "Изотретиноин".
- Isotretinoin label "آيزوتريتينوين".
- Isotretinoin label "異維A酸".
- Isotretinoin sameAs Isotretinoin.
- Isotretinoin sameAs Isotretinoína.
- Isotretinoin sameAs Isotrétinoïne.
- Isotretinoin sameAs Isotretinoina.
- Isotretinoin sameAs Isotretinoïne.
- Isotretinoin sameAs Izotretynoina.
- Isotretinoin sameAs Isotretinoína.
- Isotretinoin sameAs m.01hgfy.
- Isotretinoin sameAs Q287029.
- Isotretinoin sameAs Q287029.
- Isotretinoin sameAs isotretinoin.
- Isotretinoin sameAs DB00982.
- Isotretinoin sameAs Isotretinoin.
- Isotretinoin wasDerivedFrom Isotretinoin?oldid=606782714.
- Isotretinoin depiction Isotretinoin2DACS2.svg.
- Isotretinoin isPrimaryTopicOf Isotretinoin.