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- JWH-203 abstract "JWH-203 (1-pentyl-3-(2-chlorophenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist with approximately equal affinity at both the CB1 and CB2 receptors, having a Ki of 8.0nM at CB1 and 7.0nM at CB2. It was originally discovered by, and named after, Dr. John W. Huffman, but has subsequently been sold without his permission as an ingredient of synthetic cannabis smoking blends. Similar to the related 2'-methoxy compound JWH-250, the 2'-bromo compound JWH-249, and the 2'-methyl compound JWH-251, JWH-203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds, and has the strongest in vitro binding affinity for the cannabinoid receptors of any compound in the phenylacetyl group.Unexpectedly despite its weaker CB1 Ki in vitro, the 2-methylindole derivative JWH-204 is actually more potent than JWH-203 in animal tests for cannabinoid activity, though it is still weaker than JWH-249.".
- JWH-203 casNumber "864445-54-5".
- JWH-203 casSupplemental "(JWH-203)864445-55-6 (JWH-204)".
- JWH-203 iupacName "2-(2-chlorophenyl)-1-(1-pentylindol-3-yl)ethanone".
- JWH-203 pubchem "44397500".
- JWH-203 thumbnail JWH-203_structure.png?width=300.
- JWH-203 wikiPageID "26636686".
- JWH-203 wikiPageRevisionID "606474872".
- JWH-203 c "21".
- JWH-203 casNumber "864445".
- JWH-203 casSupplemental "864445".
- JWH-203 chemspiderid "23256082".
- JWH-203 cl "1".
- JWH-203 h "22".
- JWH-203 hasPhotoCollection JWH-203.
- JWH-203 inchi "1".
- JWH-203 inchikey "YDINKDBAZJOSLV-UHFFFAOYAH".
- JWH-203 iupacName "2".
- JWH-203 legalStatus "I-N".
- JWH-203 molecularWeight "339.858".
- JWH-203 n "1".
- JWH-203 o "1".
- JWH-203 pubchem "44397500".
- JWH-203 smiles "Clc2ccccc2CCc1cnc3ccccc13".
- JWH-203 stdinchi "1".
- JWH-203 stdinchikey "YDINKDBAZJOSLV-UHFFFAOYSA-N".
- JWH-203 verifiedrevid "451554581".
- JWH-203 subject Category:Designer_drugs.
- JWH-203 subject Category:JWH_cannabinoids.
- JWH-203 subject Category:Organochlorides.
- JWH-203 subject Category:Phenylacetylindoles.
- JWH-203 type Drug.
- JWH-203 type FunctionalSubstance.
- JWH-203 comment "JWH-203 (1-pentyl-3-(2-chlorophenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist with approximately equal affinity at both the CB1 and CB2 receptors, having a Ki of 8.0nM at CB1 and 7.0nM at CB2. It was originally discovered by, and named after, Dr. John W. Huffman, but has subsequently been sold without his permission as an ingredient of synthetic cannabis smoking blends.".
- JWH-203 label "JWH-203".
- JWH-203 label "JWH-203".
- JWH-203 label "JWH-203".
- JWH-203 sameAs JWH-203.
- JWH-203 sameAs m.0bhb8ld.
- JWH-203 sameAs Q6109214.
- JWH-203 sameAs Q6109214.
- JWH-203 wasDerivedFrom JWH-203?oldid=606474872.
- JWH-203 depiction JWH-203_structure.png.
- JWH-203 isPrimaryTopicOf JWH-203.
