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- Kelatorphan abstract "Kelatorphan is a drug which acts as a powerful and complete inhibitor of nearly all of the enzymes responsible for catabolism of the endogenous enkephalins, including neutral endopeptidase (NEP), dipeptidyl peptidase III (DPP3), aminopeptidase N (APN), and angiotensin-converting enzyme (ACE). In mice, with the intracerebroventricular co-administration of a 50 µg dose of kelatorphan (this route is necessary because kelatorphan is incapable of crossing the blood-brain-barrier) hence alongside exogenous [Met]enkephalin (ED50 approximately 10 ng), it potentiated the analgesic effects of the latter by 50,000 times. Kelatorphan also displays potent antinociceptive effects alone, and does not depress respiration, although at high doses it actually increases it.".
- Kelatorphan atcPrefix "None".
- Kelatorphan casNumber "92175-57-0".
- Kelatorphan drugbank "DB08040".
- Kelatorphan iupacName "N-[(2R)-2-benzyl-4-(hydroxyamino)-4-oxobutanoyl]-(L)-alanine".
- Kelatorphan pubchem "123982".
- Kelatorphan thumbnail Kelatorphan.svg?width=300.
- Kelatorphan wikiPageID "33861736".
- Kelatorphan wikiPageRevisionID "591990098".
- Kelatorphan atcPrefix "None".
- Kelatorphan c "14".
- Kelatorphan casNumber "92175".
- Kelatorphan chemspiderid "110501".
- Kelatorphan drugbank "DB08040".
- Kelatorphan h "18".
- Kelatorphan hasPhotoCollection Kelatorphan.
- Kelatorphan inchi "1".
- Kelatorphan inchikey "OJCFZTVYDSKXNM-GXSJLCMTBY".
- Kelatorphan iupacName "N-[-2-benzyl-4--4-oxobutanoyl]-(L)-alanine".
- Kelatorphan legalStatus "Non-regulated".
- Kelatorphan molecularWeight "294.303".
- Kelatorphan n "2".
- Kelatorphan o "5".
- Kelatorphan pubchem "123982".
- Kelatorphan smiles "O=C[C@@H]C".
- Kelatorphan stdinchi "1".
- Kelatorphan stdinchikey "OJCFZTVYDSKXNM-GXSJLCMTSA-N".
- Kelatorphan subject Category:Amines.
- Kelatorphan subject Category:Amino_acids.
- Kelatorphan subject Category:Analgesics.
- Kelatorphan subject Category:Enkephalinase_inhibitors.
- Kelatorphan subject Category:Opioids.
- Kelatorphan type Abstraction100002137.
- Kelatorphan type AliphaticCompound114601294.
- Kelatorphan type Amine114739004.
- Kelatorphan type Amines.
- Kelatorphan type AminoAcid114601829.
- Kelatorphan type AminoAcids.
- Kelatorphan type Chemical114806838.
- Kelatorphan type Compound114818238.
- Kelatorphan type Material114580897.
- Kelatorphan type Matter100020827.
- Kelatorphan type MethaneSeries114951377.
- Kelatorphan type OrganicCompound114727670.
- Kelatorphan type Part113809207.
- Kelatorphan type PhysicalEntity100001930.
- Kelatorphan type Relation100031921.
- Kelatorphan type Substance100019613.
- Kelatorphan type Drug.
- Kelatorphan type FunctionalSubstance.
- Kelatorphan comment "Kelatorphan is a drug which acts as a powerful and complete inhibitor of nearly all of the enzymes responsible for catabolism of the endogenous enkephalins, including neutral endopeptidase (NEP), dipeptidyl peptidase III (DPP3), aminopeptidase N (APN), and angiotensin-converting enzyme (ACE).".
- Kelatorphan label "Kelatorphan".
- Kelatorphan sameAs m.0hnd4ly.
- Kelatorphan sameAs Q6385498.
- Kelatorphan sameAs Q6385498.
- Kelatorphan sameAs Kelatorphan.
- Kelatorphan wasDerivedFrom Kelatorphan?oldid=591990098.
- Kelatorphan depiction Kelatorphan.svg.
- Kelatorphan isPrimaryTopicOf Kelatorphan.