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- Knockout_mouse abstract "A knockout mouse is a genetically engineered mouse in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. The loss of gene activity often causes changes in a mouse's phenotype, which includes appearance, behavior and other observable physical and biochemical characteristics.Knockout mice are important animal models for studying the role of genes which have been sequenced but whose functions have not been determined. By causing a specific gene to be inactive in the mouse, and observing any differences from normal behaviour or physiology, researchers can infer its probable function.Mice are currently the most closely related laboratory animal species to humans for which the knockout technique can easily be applied. They are widely used in knockout experiments, especially those investigating genetic questions that relate to human physiology. Gene knockout in rats is much harder and has only been possible since 2003.The first recorded knockout mouse was created by Mario R. Capecchi, Martin Evans, and Oliver Smithies in 1989, for which they were awarded the 2007 Nobel Prize in Physiology or Medicine. Aspects of the technology for generating knockout mice, and the mice themselves have been patented in many countries by private companies.".
- Knockout_mouse thumbnail Knockout_Mice5006-300.jpg?width=300.
- Knockout_mouse wikiPageExternalLink KO.
- Knockout_mouse wikiPageExternalLink www.informatics.jax.org.
- Knockout_mouse wikiPageExternalLink www.knockoutmice.org.
- Knockout_mouse wikiPageExternalLink www.knockoutmouse.org.
- Knockout_mouse wikiPageExternalLink www.komp.org.
- Knockout_mouse wikiPageExternalLink ?p=264.
- Knockout_mouse wikiPageExternalLink www.tigm.org.
- Knockout_mouse wikiPageID "33708419".
- Knockout_mouse wikiPageRevisionID "602713317".
- Knockout_mouse by "no".
- Knockout_mouse hasPhotoCollection Knockout_mouse.
- Knockout_mouse onlinebooks "no".
- Knockout_mouse subject Category:Genetically_modified_organisms.
- Knockout_mouse subject Category:Laboratory_mouse_breeds.
- Knockout_mouse type Animal100015388.
- Knockout_mouse type Chordate101466257.
- Knockout_mouse type GeneticallyModifiedOrganisms.
- Knockout_mouse type LivingThing100004258.
- Knockout_mouse type Mammal101861778.
- Knockout_mouse type Mice.
- Knockout_mouse type Mouse102330245.
- Knockout_mouse type Object100002684.
- Knockout_mouse type Organism100004475.
- Knockout_mouse type PhysicalEntity100001930.
- Knockout_mouse type Placental101886756.
- Knockout_mouse type Rodent102329401.
- Knockout_mouse type Vertebrate101471682.
- Knockout_mouse type Whole100003553.
- Knockout_mouse comment "A knockout mouse is a genetically engineered mouse in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.".
- Knockout_mouse label "Knockout mouse".
- Knockout_mouse label "Knockout-Maus".
- Knockout_mouse label "Rato knockout".
- Knockout_mouse label "Ratón knockout".
- Knockout_mouse label "Souris knock-out".
- Knockout_mouse label "Topo knockout".
- Knockout_mouse label "ノックアウトマウス".
- Knockout_mouse label "基因剔除小鼠".
- Knockout_mouse sameAs Knockout-Maus.
- Knockout_mouse sameAs Ratón_knockout.
- Knockout_mouse sameAs Souris_knock-out.
- Knockout_mouse sameAs Topo_knockout.
- Knockout_mouse sameAs ノックアウトマウス.
- Knockout_mouse sameAs Rato_knockout.
- Knockout_mouse sameAs m.01y1l_.
- Knockout_mouse sameAs Q1364740.
- Knockout_mouse sameAs Q1364740.
- Knockout_mouse sameAs Knockout_mouse.
- Knockout_mouse wasDerivedFrom Knockout_mouse?oldid=602713317.
- Knockout_mouse depiction Knockout_Mice5006-300.jpg.
- Knockout_mouse isPrimaryTopicOf Knockout_mouse.
