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- LACTB abstract "Serine beta-lactamase-like protein LACTB, mitochondrial is an enzyme that in humans is encoded by the LACTB gene.This gene encodes a 54 kDa protein sharing significant sequence similarity to serine proteases of the penicillin binding protein and beta-lactamase superfamily occurring in bacteria.The amino acid residues necessary for serine protease activity in the bacterial penicillin binding proteins are conserved in LACTB indicating that LACTB has enzymatic activity although its enzymatic substrate remains unknown. LACTB is localized in the mitochondrial intermembrane space between the outer and inner mitochondrial membranes, and can polymerize into filaments that can be visualized by transmission electron microscopy.Phylogenetic profiling shows that LACTB is associated with the mitochondrial respiratory complex I. Gene network analyses demonstrate a causative link between LACTB and obesity.".
- LACTB entrezgene "114294".
- LACTB wikiPageID "16845887".
- LACTB wikiPageRevisionID "596018055".
- LACTB hasPhotoCollection LACTB.
- LACTB requireManualInspection "no".
- LACTB summaryText "This gene encodes a 54 kDa protein sharing significant sequence similarity to serine proteases of the penicillin binding protein and beta-lactamase superfamily occurring in bacteria. The amino acid residues necessary for serine protease activity in the bacterial penicillin binding proteins are conserved in LACTB indicating that LACTB has enzymatic activity although its enzymatic substrate remains unknown. LACTB is localized in the mitochondrial intermembrane space between the outer and inner mitochondrial membranes, and can polymerize into filaments that can be visualized by transmission electron microscopy. Phylogenetic profiling shows that LACTB is associated with the mitochondrial respiratory complex I. Gene network analyses demonstrate a causative link between LACTB and obesity.".
- LACTB updateCitations "yes".
- LACTB updatePage "yes".
- LACTB updateProteinBox "yes".
- LACTB updateSummary "yes".
- LACTB type Biomolecule.
- LACTB type Protein.
- LACTB type BiologicalObject.
- LACTB comment "Serine beta-lactamase-like protein LACTB, mitochondrial is an enzyme that in humans is encoded by the LACTB gene.This gene encodes a 54 kDa protein sharing significant sequence similarity to serine proteases of the penicillin binding protein and beta-lactamase superfamily occurring in bacteria.The amino acid residues necessary for serine protease activity in the bacterial penicillin binding proteins are conserved in LACTB indicating that LACTB has enzymatic activity although its enzymatic substrate remains unknown. ".
- LACTB label "LACTB".
- LACTB sameAs m.04083g5.
- LACTB sameAs Q6456952.
- LACTB sameAs Q6456952.
- LACTB wasDerivedFrom LACTB?oldid=596018055.
- LACTB isPrimaryTopicOf LACTB.