Matches in DBpedia 2014 for { <http://dbpedia.org/resource/LATS2> ?p ?o. }
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- LATS2 abstract "Serine/threonine-protein kinase LATS2 is an enzyme that in humans is encoded by the LATS2 gene.This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.".
- LATS2 entrezgene "26524".
- LATS2 wikiPageID "14877574".
- LATS2 wikiPageRevisionID "592158226".
- LATS2 hasPhotoCollection LATS2.
- LATS2 requireManualInspection "no".
- LATS2 summaryText "This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.".
- LATS2 updateCitations "yes".
- LATS2 updatePage "yes".
- LATS2 updateProteinBox "yes".
- LATS2 updateSummary "yes".
- LATS2 type Biomolecule.
- LATS2 type Protein.
- LATS2 type BiologicalObject.
- LATS2 comment "Serine/threonine-protein kinase LATS2 is an enzyme that in humans is encoded by the LATS2 gene.This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis.".
- LATS2 label "LATS2".
- LATS2 sameAs m.03g_ztq.
- LATS2 sameAs Q6457140.
- LATS2 sameAs Q6457140.
- LATS2 wasDerivedFrom LATS2?oldid=592158226.
- LATS2 isPrimaryTopicOf LATS2.