Matches in DBpedia 2014 for { <http://dbpedia.org/resource/LECT1> ?p ?o. }
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- LECT1 abstract "Chondromodulin-1 is a protein that in humans is encoded by the LECT1 gene.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.".
- LECT1 entrezgene "11061".
- LECT1 wikiPageID "15182705".
- LECT1 wikiPageRevisionID "592164661".
- LECT1 hasPhotoCollection LECT1.
- LECT1 requireManualInspection "no".
- LECT1 summaryText "This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.".
- LECT1 updateCitations "yes".
- LECT1 updatePage "yes".
- LECT1 updateProteinBox "yes".
- LECT1 updateSummary "yes".
- LECT1 type Biomolecule.
- LECT1 type Protein.
- LECT1 type BiologicalObject.
- LECT1 comment "Chondromodulin-1 is a protein that in humans is encoded by the LECT1 gene.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it.".
- LECT1 label "LECT1".
- LECT1 sameAs m.03hl4bd.
- LECT1 sameAs Q15996751.
- LECT1 sameAs Q15996751.
- LECT1 wasDerivedFrom LECT1?oldid=592164661.
- LECT1 isPrimaryTopicOf LECT1.