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- Lactate_shuttle abstract "The lactate shuttle is a hypothesis proposed by professor George Brooks of the University of California at Berkeley, describing the movement of lactate intracellularly and intercellularly (cell-cell). The hypothesis is based on the observation that lactate is formed and utilized continuously in diverse cells under both anaerobic and aerobic conditions. Further, lactate produced at sites with high rates of glycolysis and glycogenolysis can be shuttled to adjacent or remote sites including heart or other skeletal muscles where the lactate can be used as a gluconeogenic precursor or substrate for oxidation.In addition to its role as a fuel source predominantly in the muscles, heart, brain, and liver, the lactate shuttle hypothesis also relates the role of lactate in redox signalling, gene expression, and lipolytic control. These additional roles of lactate have given rise to the term ‘lactormone’, pertaining to the role of lactate as a signalling hormone.".
- Lactate_shuttle wikiPageID "39047203".
- Lactate_shuttle wikiPageRevisionID "595420681".
- Lactate_shuttle subject Category:Cancer_research.
- Lactate_shuttle subject Category:Gene_expression.
- Lactate_shuttle subject Category:Hormones.
- Lactate_shuttle comment "The lactate shuttle is a hypothesis proposed by professor George Brooks of the University of California at Berkeley, describing the movement of lactate intracellularly and intercellularly (cell-cell). The hypothesis is based on the observation that lactate is formed and utilized continuously in diverse cells under both anaerobic and aerobic conditions.".
- Lactate_shuttle label "Lactate shuttle".
- Lactate_shuttle sameAs m.0t52f4j.
- Lactate_shuttle sameAs Q17157037.
- Lactate_shuttle sameAs Q17157037.
- Lactate_shuttle wasDerivedFrom Lactate_shuttle?oldid=595420681.
- Lactate_shuttle isPrimaryTopicOf Lactate_shuttle.