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- Lead_compound abstract "A lead compound (i.e. a "leading" compound, not lead metal) in drug discovery is a chemical compound that has pharmacological or biological activity likely to be therapeutically useful, but may still have suboptimal structure that requires modification to fit better to the target. Its chemical structure is used as a starting point for chemical modifications in order to improve potency, selectivity, or pharmacokinetic parameters. Furthermore, newly invented pharmacologically active moieties may have poor druglikeness and may require chemical modification to become drug-like enough to be tested biologically or clinically.".
- Lead_compound wikiPageID "11085533".
- Lead_compound wikiPageRevisionID "606695900".
- Lead_compound hasPhotoCollection Lead_compound.
- Lead_compound subject Category:Chemical_compounds.
- Lead_compound type Abstraction100002137.
- Lead_compound type Cognition100023271.
- Lead_compound type Compound105870180.
- Lead_compound type Concept105835747.
- Lead_compound type Content105809192.
- Lead_compound type Idea105833840.
- Lead_compound type LeadCompounds.
- Lead_compound type PsychologicalFeature100023100.
- Lead_compound type Whole105869584.
- Lead_compound comment "A lead compound (i.e. a "leading" compound, not lead metal) in drug discovery is a chemical compound that has pharmacological or biological activity likely to be therapeutically useful, but may still have suboptimal structure that requires modification to fit better to the target. Its chemical structure is used as a starting point for chemical modifications in order to improve potency, selectivity, or pharmacokinetic parameters.".
- Lead_compound label "Lead compound".
- Lead_compound label "Leitstruktur (Pharmakologie)".
- Lead_compound label "リード化合物".
- Lead_compound label "先导化合物".
- Lead_compound sameAs Leitstruktur_(Pharmakologie).
- Lead_compound sameAs リード化合物.
- Lead_compound sameAs m.02q_jjq.
- Lead_compound sameAs Q903238.
- Lead_compound sameAs Q903238.
- Lead_compound sameAs Lead_compound.
- Lead_compound wasDerivedFrom Lead_compound?oldid=606695900.
- Lead_compound isPrimaryTopicOf Lead_compound.