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- Lectin_pathway abstract "The lectin pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, in that, after activation, it proceeds through the action of C4 and C2 to produce activated complement proteins further down the cascade. In contrast to the classical complement pathway, the lectin pathway does not recognize antibody bound to its target. The lectin pathway starts with mannose-binding lectin or ficolin binding to certain sugars.In this pathway, mannose-binding lectin binds to mannose, glucose or other sugars with 3- and 4-OH groups placed in the equatorial plane, in terminal positions on carbohydrate or glycoprotein components of microorganisms including bacteria such as Salmonella, Listeria, and Neisseria strains. Fungal pathogens such as Candida albicans and Cryptococcus neoformans as well as some viruses such as HIV-1 and Respiratory syncytial virus (RSV) are bound by MBL. Mannan-binding lectin (MBL, also called mannose-binding protein) is a protein belonging to the collectin family that is produced by the liver and can initiate the complement cascade by binding to pathogen surfaces.".
- Lectin_pathway thumbnail Mannose_structure.svg?width=300.
- Lectin_pathway wikiPageExternalLink complement.htm.
- Lectin_pathway wikiPageID "4400113".
- Lectin_pathway wikiPageRevisionID "602171015".
- Lectin_pathway hasPhotoCollection Lectin_pathway.
- Lectin_pathway subject Category:Complement_system.
- Lectin_pathway comment "The lectin pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, in that, after activation, it proceeds through the action of C4 and C2 to produce activated complement proteins further down the cascade. In contrast to the classical complement pathway, the lectin pathway does not recognize antibody bound to its target.".
- Lectin_pathway label "Lectin pathway".
- Lectin_pathway label "Лектиновый путь активации системы комплемента".
- Lectin_pathway sameAs Lintasan_MBL.
- Lectin_pathway sameAs m.0c05sv.
- Lectin_pathway sameAs Q4216356.
- Lectin_pathway sameAs Q4216356.
- Lectin_pathway wasDerivedFrom Lectin_pathway?oldid=602171015.
- Lectin_pathway depiction Mannose_structure.svg.
- Lectin_pathway isPrimaryTopicOf Lectin_pathway.
