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- Lipid-binding_serum_glycoprotein abstract "In molecular biology, the lipid-binding serum glycoproteins family, also known as the BPI/LBP/Plunc family or LBP/BPI/CETP family represents a family which includes mammalian lipid-binding serum glycoproteins. Members of this family include:Bactericidal permeability-increasing protein (BPI)Lipopolysaccharide-binding protein (LBP)Cholesteryl ester transfer protein (CETP)Phospholipid transfer protein (PLTP)Palate, lung and nasal epithelium carcinoma-associated protein (PLUNC)These proteins consist of N- and C-terminal domains, which share a similar two-layer alpha/beta structure, but show little sequence identity to each other.Bactericidal permeability-increasing protein (BPI) is a potent antimicrobial protein of 456 amino acids that binds to and neutralises lipopolysaccharides from the outer membrane of Gram-negative bacteria. BPI contains two domains that adopt the same structural fold, even though they have little sequence similarity.Lipopolysaccharide-binding protein (LBP) is an endotoxin-binding protein that is closely related to, and functions in a co-ordinated manner with BPI to facilitate an integrated host response to invading Gram-negative bacteria.Cholesteryl ester transfer protein (CETP) is a glycoprotein that facilitates the transfer of lipids (cholesteryl esters and triglycerides) between the different lipoproteins that transport them through plasma, including HDL, LDL, VLDL and chylomicrons. These lipoproteins shield the lipids from water by encapsulating them within a coating of polar lipids and proteins.Phospholipid transfer protein (PLTP) exchanges phospholipids between lipoproteins and remodels high-density lipoproteins (HDLs).Palate, lung and nasal epithelium carcinoma-associated protein (PLUNC) is a potential host defensive protein that is secreted from the submucosal gland to the saliva and nasal lavage fluid. PLUNC appears to be a secreted product of neutrophil granules that participates in an aspect of the inflammatory response that contributes to host defence. Short palate, lung and nasal epithelium clone 1 (SPLUNC1) may bind the lipopolysaccharide of Gram-negative nanobacteria, thereby playing an important role in the host defence of nasopharyngeal epithelium.".
- Lipid-binding_serum_glycoprotein symbol "LBP_BPI_CETP".
- Lipid-binding_serum_glycoprotein symbol "LBP_BPI_CETP_C".
- Lipid-binding_serum_glycoprotein thumbnail PDB_1bp1_EBI.jpg?width=300.
- Lipid-binding_serum_glycoprotein wikiPageID "29159565".
- Lipid-binding_serum_glycoprotein wikiPageRevisionID "592199216".
- Lipid-binding_serum_glycoprotein caption "crystal structure of bpi, the human bactericidal permeability-increasing protein".
- Lipid-binding_serum_glycoprotein hasPhotoCollection Lipid-binding_serum_glycoprotein.
- Lipid-binding_serum_glycoprotein interpro "IPR001124".
- Lipid-binding_serum_glycoprotein interpro "IPR017942".
- Lipid-binding_serum_glycoprotein name "LBP / BPI / CETP family, C-terminal domain".
- Lipid-binding_serum_glycoprotein name "LBP / BPI / CETP family, N-terminal domain".
- Lipid-binding_serum_glycoprotein opmFamily "452".
- Lipid-binding_serum_glycoprotein opmProtein "2".
- Lipid-binding_serum_glycoprotein pfam "PF01273".
- Lipid-binding_serum_glycoprotein pfam "PF02886".
- Lipid-binding_serum_glycoprotein prosite "PDOC00367".
- Lipid-binding_serum_glycoprotein scop "1".
- Lipid-binding_serum_glycoprotein symbol "LBP_BPI_CETP".
- Lipid-binding_serum_glycoprotein symbol "LBP_BPI_CETP_C".
- Lipid-binding_serum_glycoprotein tcdb "1".
- Lipid-binding_serum_glycoprotein subject Category:Peripheral_membrane_proteins.
- Lipid-binding_serum_glycoprotein subject Category:Protein_domains.
- Lipid-binding_serum_glycoprotein subject Category:Protein_families.
- Lipid-binding_serum_glycoprotein subject Category:Water-soluble_transporters.
- Lipid-binding_serum_glycoprotein type Abstraction100002137.
- Lipid-binding_serum_glycoprotein type Attribute100024264.
- Lipid-binding_serum_glycoprotein type Chemical114806838.
- Lipid-binding_serum_glycoprotein type Compound114818238.
- Lipid-binding_serum_glycoprotein type Environment113934596.
- Lipid-binding_serum_glycoprotein type Macromolecule114944888.
- Lipid-binding_serum_glycoprotein type Material114580897.
- Lipid-binding_serum_glycoprotein type Matter100020827.
- Lipid-binding_serum_glycoprotein type Molecule114682133.
- Lipid-binding_serum_glycoprotein type OrganicCompound114727670.
- Lipid-binding_serum_glycoprotein type Part113809207.
- Lipid-binding_serum_glycoprotein type PeripheralMembraneProteins.
- Lipid-binding_serum_glycoprotein type PhysicalEntity100001930.
- Lipid-binding_serum_glycoprotein type Protein114728724.
- Lipid-binding_serum_glycoprotein type ProteinDomains.
- Lipid-binding_serum_glycoprotein type Relation100031921.
- Lipid-binding_serum_glycoprotein type Situation113927383.
- Lipid-binding_serum_glycoprotein type Sphere114514039.
- Lipid-binding_serum_glycoprotein type State100024720.
- Lipid-binding_serum_glycoprotein type Substance100019613.
- Lipid-binding_serum_glycoprotein type Thing100002452.
- Lipid-binding_serum_glycoprotein type Unit109465459.
- Lipid-binding_serum_glycoprotein type Biomolecule.
- Lipid-binding_serum_glycoprotein type Protein.
- Lipid-binding_serum_glycoprotein type BiologicalObject.
- Lipid-binding_serum_glycoprotein comment "In molecular biology, the lipid-binding serum glycoproteins family, also known as the BPI/LBP/Plunc family or LBP/BPI/CETP family represents a family which includes mammalian lipid-binding serum glycoproteins.".
- Lipid-binding_serum_glycoprotein label "Lipid-binding serum glycoprotein".
- Lipid-binding_serum_glycoprotein sameAs m.0dlmrxz.
- Lipid-binding_serum_glycoprotein sameAs Q6556353.
- Lipid-binding_serum_glycoprotein sameAs Q6556353.
- Lipid-binding_serum_glycoprotein sameAs Lipid-binding_serum_glycoprotein.
- Lipid-binding_serum_glycoprotein wasDerivedFrom Lipid-binding_serum_glycoprotein?oldid=592199216.
- Lipid-binding_serum_glycoprotein depiction PDB_1bp1_EBI.jpg.
- Lipid-binding_serum_glycoprotein isPrimaryTopicOf Lipid-binding_serum_glycoprotein.
