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- Lipidomics abstract "Lipidomics is the large-scale study of pathways and networks of cellular lipids in biological systems The word "lipidome" is used to describe the complete lipid profile within a cell, tissue or organism and is a subset of the "metabolome" which also includes the three other major classes of biological molecules: proteins/amino-acids, sugars and nucleic acids. Lipidomics is a relatively recent research field that has been driven by rapid advances in technologies such as mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, fluorescence spectroscopy, dual polarisation interferometry and computational methods, coupled with the recognition of the role of lipids in many metabolic diseases such as obesity, atherosclerosis, stroke, hypertension and diabetes. This rapidly expanding field complements the huge progress made in genomics and proteomics, all of which constitute the family of systems biology.Lipidomics research involves the identification and quantification of the thousands of cellular lipid molecular species and their interactions with other lipids, proteins, and other metabolites. Investigators in lipidomics examine the structures, functions, interactions, and dynamics of cellular lipids and the changes that occur during perturbation of the system.Han and Gross first defined the field of lipidomics through integrating the specific chemical properties inherent in lipid molecular species with a comprehensive mass spectrometric approach. Although lipidomics is under the umbrella of the more general field of "metabolomics", lipidomics is itself a distinct discipline due to the uniqueness and functional specificity of lipids relative to other metabolites.In lipidomic research, a vast amount of information quantitatively describing the spatial and temporal alterations in the content and composition of different lipid molecular species is accrued after perturbation of a cell through changes in its physiological or pathological state. Information obtained from these studies facilitates mechanistic insights into changes in cellular function. Therefore, lipidomic studies play an essential role in defining the biochemical mechanisms of lipid-related disease processes through identifying alterations in cellular lipid metabolism, trafficking and homeostasis. The growing attention on lipid research is also seen from the initiatives underway of the LIPID Metabolites And Pathways Strategy (LIPID MAPS Consortium). and The European Lipidomics Initiative (ELIfe).".
- Lipidomics thumbnail Metabolomics_schema.png?width=300.
- Lipidomics wikiPageExternalLink lipidomics.html.
- Lipidomics wikiPageExternalLink www.lipidlibrary.co.uk.
- Lipidomics wikiPageExternalLink www.lipidmaps.org.
- Lipidomics wikiPageExternalLink www.lipidomics.net.
- Lipidomics wikiPageExternalLink www.lpath.com.
- Lipidomics wikiPageID "884805".
- Lipidomics wikiPageRevisionID "600986448".
- Lipidomics hasPhotoCollection Lipidomics.
- Lipidomics subject Category:Biochemistry_methods.
- Lipidomics subject Category:Biotechnology.
- Lipidomics subject Category:Lipids.
- Lipidomics type Ability105616246.
- Lipidomics type Abstraction100002137.
- Lipidomics type BiochemistryMethods.
- Lipidomics type Chemical114806838.
- Lipidomics type Cognition100023271.
- Lipidomics type Compound114818238.
- Lipidomics type Know-how105616786.
- Lipidomics type Lipid114938907.
- Lipidomics type Lipids.
- Lipidomics type Macromolecule114944888.
- Lipidomics type Material114580897.
- Lipidomics type Matter100020827.
- Lipidomics type Method105660268.
- Lipidomics type Molecule114682133.
- Lipidomics type OrganicCompound114727670.
- Lipidomics type Part113809207.
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- Lipidomics type PsychologicalFeature100023100.
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- Lipidomics type Unit109465459.
- Lipidomics comment "Lipidomics is the large-scale study of pathways and networks of cellular lipids in biological systems The word "lipidome" is used to describe the complete lipid profile within a cell, tissue or organism and is a subset of the "metabolome" which also includes the three other major classes of biological molecules: proteins/amino-acids, sugars and nucleic acids.".
- Lipidomics label "Lipidomics".
- Lipidomics sameAs m.03lns3.
- Lipidomics sameAs Q6556376.
- Lipidomics sameAs Q6556376.
- Lipidomics sameAs Lipidomics.
- Lipidomics wasDerivedFrom Lipidomics?oldid=600986448.
- Lipidomics depiction Metabolomics_schema.png.
- Lipidomics isPrimaryTopicOf Lipidomics.
