Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MAP2K4> ?p ?o. }
Showing items 1 to 21 of
21
with 100 items per page.
- MAP2K4 abstract "Dual specificity mitogen-activated protein kinase kinase 4 is an enzyme that in humans is encoded by the MAP2K4 gene.This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK1. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.".
- MAP2K4 entrezgene "6416".
- MAP2K4 wikiPageID "14118929".
- MAP2K4 wikiPageRevisionID "592357026".
- MAP2K4 hasPhotoCollection MAP2K4.
- MAP2K4 requireManualInspection "no".
- MAP2K4 summaryText "This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK1. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.".
- MAP2K4 updateCitations "yes".
- MAP2K4 updatePage "yes".
- MAP2K4 updateProteinBox "yes".
- MAP2K4 updateSummary "yes".
- MAP2K4 type Biomolecule.
- MAP2K4 type Protein.
- MAP2K4 type BiologicalObject.
- MAP2K4 comment "Dual specificity mitogen-activated protein kinase kinase 4 is an enzyme that in humans is encoded by the MAP2K4 gene.This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK1.".
- MAP2K4 label "MAP2K4".
- MAP2K4 sameAs m.03cv5fp.
- MAP2K4 sameAs Q6714347.
- MAP2K4 sameAs Q6714347.
- MAP2K4 wasDerivedFrom MAP2K4?oldid=592357026.
- MAP2K4 isPrimaryTopicOf MAP2K4.